The Molecular Diversity of 1H-Indole-3-Carbaldehyde Derivatives and Their Role in Multicomponent Reactions

被引：13

作者：

Mohammadi Ziarani, Ghodsi ^{[1
]}

Hasani, Samira ^{[1
]}

Mohajer, Fatemeh ^{[1
]}

Varma, Rajender S. ^{[2
]}

Rafiee, Fatemeh ^{[1
]}

机构：

[1] Alzahra Univ, Fac Phys & Chem, Dept Chem, POB 1993893973, Tehran, Iran

[2] Palacky Univ, Reg Ctr Adv Technol & Mat, Czech Adv Technol & Res Inst, Slechtitelu 27, Olomouc 78371, Czech Republic

来源：

TOPICS IN CURRENT CHEMISTRY | 2022年 / 380卷 / 04期

关键词：

Multicomponent reactions; 1H-Indole-3-carbaldehyde; Heterocycles; Carbazole derivatives; Triazole derivatives; Pyrimidine derivatives; ONE-POT SYNTHESIS; MEDIATED ONE-POT; INDOLE-DERIVATIVES; HETEROCYCLIC-COMPOUNDS; ANTICANCER ACTIVITY; BIOLOGICAL-ACTIVITIES; FACILE SYNTHESIS; ACIDS; ANTIOXIDANT; INHIBITORS;

D O I：

10.1007/s41061-022-00379-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1H-Indole-3-carbaldehyde and related members of the indole family are ideal precursors for the synthesis of active molecules. 1H-Indole-3-carbaldehyde and its derivatives are essential and efficient chemical precursors for generating biologically active structures. Multicomponent reactions (MCRs) offer access to complex molecules. This review highlights the recent applications of 1H-indole-3-carbaldehyde in such inherently sustainable multicomponent reactions from the period, 2014 to 2021 and provides an overview of the field that awaits further exploitation in the assembly of pharmaceutically interesting scaffolds. [GRAPHICS] .

引用

页数：37

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