Novel Graphical Representation and Numerical Characterization of DNA Sequences

被引：10

作者：

Li, Chun ^{[1
,2
]}

Fei, Wenchao ^{[1
]}

Zhao, Yan ^{[1
]}

Yu, Xiaoqing ^{[3
]}

机构：

[1] Bohai Univ, Dept Math, Jinzhou 121013, Peoples R China

[2] Bohai Univ, Food Sci Res Inst, Jinzhou 121013, Peoples R China

[3] Shanghai Inst Technol, Dept Appl Math, Shanghai 201418, Peoples R China

来源：

APPLIED SCIENCES-BASEL | 2016年 / 6卷 / 03期

基金：

中国国家自然科学基金;

关键词：

numerical characterization; graphical representation; cell-based vector; phylogenetic analysis; 2-combination; SIMILARITY ANALYSIS; CURVE; TOOL;

D O I：

10.3390/app6030063

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Modern sequencing technique has provided a wealth of data on DNA sequences, which has made the analysis and comparison of sequences a very important but difficult task. In this paper, by regarding the dinucleotide as a 2-combination of the multiset [GRAPHICS] , a novel 3-D graphical representation of a DNA sequence is proposed, and its projections on planes (x,y), (y,z) and (x,z) are also discussed. In addition, based on the idea of "piecewise function", a cell-based descriptor vector is constructed to numerically characterize the DNA sequence. The utility of our approach is illustrated by the examination of phylogenetic analysis on four datasets.

引用

页数：15

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