Does Def6 Deficiency Cause Autoimmunity?

被引:6
作者
Altman, Amnon [1 ]
Becart, Stephane [1 ]
机构
[1] La Jolla Inst Allergy & Immunol, La Jolla, CA 92037 USA
关键词
TRANSCRIPTION FACTOR; PROTEIN; CELLS;
D O I
10.1016/j.immuni.2009.06.013
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:1 / 2
页数:2
相关论文
共 10 条
[1]   Tyrosine-Phosphorylation-Dependent Translocation of the SLAT Protein to the Immunological Synapse Is Required for NFAT Transcription Factor Activation [J].
Becart, Stephane ;
Balancio, Ann J. Canonigo ;
Charvet, Celine ;
Feau, Sonia ;
Sedwick, Caitlin E. ;
Altman, Amnon .
IMMUNITY, 2008, 29 (05) :704-719
[2]   SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling [J].
Becart, Stephane ;
Charvet, Celine ;
Balancio, Ann J. Canonigo ;
De Trez, Carl ;
Tanaka, Yoshihiko ;
Duan, Wei ;
Ware, Carl ;
Croft, Michael ;
Altman, Amnon .
JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (08) :2164-2175
[3]   The development of inflammatory TH-17 cells requires interferon-regulatory factor 4 [J].
Bruestle, Anne ;
Heink, Sylvia ;
Huber, Magdalena ;
Rosenplaenter, Christine ;
Stadelmann, Christine ;
Yu, Philipp ;
Arpaia, Enrico ;
Mak, Tak W. ;
Kamradt, Thomas ;
Lohoff, Michael .
NATURE IMMUNOLOGY, 2007, 8 (09) :958-966
[4]   Spontaneous autoimmunity in 129 and C57BL/6 mice - Implications for autoimmunity described in gene-targeted mice [J].
Bygrave, AE ;
Rose, KL ;
Cortes-Hernandez, J ;
Warren, J ;
Rigby, RJ ;
Cook, HT ;
Walport, MJ ;
Vyse, TJ ;
Botto, M .
PLOS BIOLOGY, 2004, 2 (08) :1081-1090
[5]   IRF-4-Binding Protein Inhibits Interleukin-17 and Interleukin-21 Production by Controlling the Activity of IRF-4 Transcription Factor [J].
Chen, Qinzhong ;
Yang, Wen ;
Gupta, Sanjay ;
Biswas, Partha ;
Smith, Paula ;
Bhagat, Govind ;
Pernis, Alessandra B. .
IMMUNITY, 2008, 29 (06) :899-911
[6]   Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity [J].
Fanzo, JC ;
Yang, W ;
Jang, SY ;
Gupta, S ;
Chen, QZ ;
Siddiq, A ;
Greenberg, S ;
Pernis, AB .
JOURNAL OF CLINICAL INVESTIGATION, 2006, 116 (03) :703-714
[7]   Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system [J].
Gupta, S ;
Lee, A ;
Hu, CM ;
Fanzo, J ;
Goldberg, I ;
Cattoretti, G ;
Pernis, AB .
HUMAN IMMUNOLOGY, 2003, 64 (04) :389-401
[8]   The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells [J].
Ivanov, Ivaylo I. ;
McKenzie, Brent S. ;
Zhou, Liang ;
Tadokoro, Carlos E. ;
Lepelley, Alice ;
Lafaille, Juan J. ;
Cua, Daniel J. ;
Littman, Dan R. .
CELL, 2006, 126 (06) :1121-1133
[9]   SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells [J].
Tanaka, Y ;
Bi, K ;
Kitamura, R ;
Hong, SJ ;
Altman, Y ;
Matsumoto, A ;
Tabata, H ;
Lebedeva, S ;
Bushway, PJ ;
Altman, A .
IMMUNITY, 2003, 18 (03) :403-414
[10]   Molecular antagonism and plasticity of regulatory and inflammatory T cell programs [J].
Yang, Xuexian O. ;
Nurieva, Roza ;
Martinez, Gustavo J. ;
Kang, Hong Soon ;
Chung, Yeonseok ;
Pappu, Bhanu P. ;
Shah, Bhavin ;
Chang, Seon Hee ;
Schluns, Kimberly S. ;
Watowich, Stephanie S. ;
Feng, Xin-Hua ;
Jetten, Anton M. ;
Dong, Chen .
IMMUNITY, 2008, 29 (01) :44-56