Rhodium(III)-Catalyzed Addition of Indoles with Boc-Imines via C-H Bond Activation

被引：4
|
作者：
Wang, Jinfang [1 ]
Wang, Hui [2 ]
Yue, Chuanjun [1 ]
机构：
[1] Changzhou Inst Technol, 666 Liao He Rd, Changzhou 213032, Jiangsu, Peoples R China
[2] Changzhou Le Sun Pharmaceut Ltd, 518 Yun He Rd, Changzhou 213125, Jiangsu, Peoples R China
来源：
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2018年 / 29卷 / 06期
关键词：
rhodium(III)-catalysis; C-H activation; indole; BETA-AMINO ACIDS; ENANTIOSELECTIVE SYNTHESIS; ALKALOIDS; ALKYNES;
D O I：
10.21577/0103-5053.20170212
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A rhodium-catalyzed alkylation reaction of indoles with N-Boc-imines has been developed via C-H activation to afford a series of substituted 2-indolyl-methanamine derivatives with good functional group tolerance and regioselectivity. A wide range of indole-based alkylation products could be obtained in up to 95% yield.
引用
收藏
页码：1175 / 1182
页数：8
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