DEEP BRAIN STIMULATION FOR THE TREATMENT OF EPILEPSY

被引：41

作者：

Hamani, Clement ^{[1
]}

Andrade, Danielle ^{[2
]}

Hodaie, Mojgan ^{[1
]}

Wennberg, Richard ^{[2
]}

Lozano, Andres ^{[1
]}

机构：

[1] Univ Toronto, Toronto Western Hosp, Div Neurosurg, Toronto, ON M5T 2S8, Canada

[2] Univ Toronto, Toronto Western Hosp, Div Neurol, Toronto, ON M5T 2S8, Canada

来源：

INTERNATIONAL JOURNAL OF NEURAL SYSTEMS | 2009年 / 19卷 / 03期

关键词：

Epilepsy; deep brain stimulation; thalamus; hippocampus; closed-loop; open-loop; CHRONIC ELECTRICAL-STIMULATION; CENTROMEDIAN THALAMIC NUCLEUS; HIGH-FREQUENCY STIMULATION; CHRONIC CEREBELLAR STIMULATION; INTRACTABLE SEIZURE PATTERNS; PILOCARPINE-INDUCED SEIZURES; AMYGDALA-KINDLED SEIZURES; CLOSED-LOOP STIMULATION; TEMPORAL-LOBE SEIZURES; TERM-FOLLOW-UP;

D O I：

10.1142/S0129065709001975

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

During the last decade, deep brain stimulation (DBS) has been used to treat several neurologic disorders, including epilepsy. Promising results have been reported with stimulation in different brain regions. At present however, several issues remain unanswered. As an example, it is still unclear whether particular seizure types and syndromes should be treated with DBS in different targets or with different stimulation parameters. In addition, clinical, electrophysiological and anatomical features capable of predicting a good postoperative outcome are still unknown. We review the published literature on DBS, cortical and cerebellar stimulation for the treatment of epilepsy focusing predominantly on the rationale and clinical outcome in each target.

引用

页码：213 / 226

页数：14

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