KLEBSIELLA PNEUMONIAE CARBAPENEMASE-PRODUCING KLEBSIELLA PNEUMONIAE IN THE INTENSIVE CARE UNIT: A REAL CHALLENGE TO PHYSICIANS, SCIENTIFIC COMMUNITY, AND SOCIETY

被引：10

作者：

Carvalhaes, Cecilia Godoy ^{[1
]}

Cayo, Rodrigo ^{[1
]}

Gales, Ana Cristina ^{[1
]}

机构：

[1] Univ Fed Sao Paulo, UNIFESP, Lab Alerta, Disciplina Infectol,Dept Med, BR-04039032 Sao Paulo, Brazil

来源：

SHOCK | 2013年 / 39卷 / 07期

关键词：

MDR pathogens; KPC; antimicrobial resistance; fitness cost; mortality; DESORPTION IONIZATION-TIME; HYDROLYZING BETA-LACTAMASE; NEW-YORK; PSEUDOMONAS-AERUGINOSA; ANTIBIOTIC-RESISTANCE; PROLONGED-INFUSION; EMERGENCE; OUTBREAK; EPIDEMIOLOGY; ACQUISITION;

D O I：

10.1097/SHK.0b013e31828faf1f

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The prevalence of multidrug-resistant pathogens, especially in intensive care units, has increased and represents a great concern for medical and scientific community. Infections caused by these pathogens are associated with increased costs, length of hospitalization, and morbidity/mortality rates. The last decade was marked by the spread of carbapenem resistance determinants especially in Enterobacteriaceae isolates. In this review, the Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae is used as an example to discuss the difficulties in dealing with multidrug-resistant pathogens in the intensive care unit setting and how they represent a challenge to the medical-scientific community and, ultimately, the whole society.

引用

页码：32 / 37

页数：6

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