Novel bioactive peptides sequences released by in vitro digestion of proteins isolated from Amaranthus hypochondriacus

被引：12
|
作者：
Ayala-Nino, Alexis [1 ]
Castaneda-Ovando, Araceli [1 ]
Jaimez-Ordaz, Judith [1 ]
Rodriguez-Serrano, Gabriela Mariana [2 ]
Sanchez-Franco, Jose Antonio [3 ]
Gonzalez-Olivares, Luis Guillermo [1 ]
机构：
[1] Univ Autonoma Estado Hidalgo, Chem Invest Ctr, Mineral De La Reforma, Hidalgo, Mexico
[2] Univ Autonoma Metropolitana Iztapalapa, Biotechnol Dept, Mexico City, DF, Mexico
[3] Univ Autonoma Estado Mexico, Ejidos Santa Catarina, Unidad Acad Profes, Acolman, Edo De Mexico, Mexico
来源：
NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 13期
关键词：
In vitro digestion; antihypertensive activity; antithrombotic activity; antioxidant activity; amaranth proteins; bioactive peptides;
D O I：
10.1080/14786419.2020.1862837
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Amaranth is a protein-rich seed, highly consumed in Mexico and reported as a potential source of bio-peptides with physiological function. Therefore, the objective of this study was to evaluate and identify bioactive peptide sequences from amaranth protein fractions released by pepsin and pancreatin in vitro digestion. Multifunctional bioactivities of peptides were measured through antihypertensive, antithrombotic and antioxidant assays. Peptide sequences were identified by analysis with a Nano-LC-ESI-MS/MS. With these results, it was demonstrated that the in vitro enzymatic digestion mechanism allows the release of multifunctional bioactive peptide fractions from amaranth proteins.
引用
收藏
页码：3485 / 3488
页数：4
相关论文
共 50 条
  • [1] Characterization of bioactive peptides in Amaranthus hypochondriacus seed storage proteins.
    Silva-Sanchez, C
    de Mejia, E
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U43 - U43
  • [2] Bioactive peptides in amaranth (Amaranthus hypochondriacus) seed
    Silva-Sanchez, C.
    de la Rosa, A. P. Barba
    Leon-Galvan, M. F.
    de Lumen, B. O.
    de Leon-Rodriguez, A.
    de Mejia, E. Gonzalez
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2008, 56 (04) : 1233 - 1240
  • [3] Sequence Identification of Bioactive Peptides from Amaranth Seed Proteins (Amaranthus hypochondriacus spp.)
    Ayala-Nino, Alexis
    Mariana Rodriguez-Serrano, Gabriela
    Guillermo Gonzalez-Olivares, Luis
    Contreras-Lopez, Elizabeth
    Regal-Lopez, Patricia
    Cepeda-Saez, Alberto
    MOLECULES, 2019, 24 (17):
  • [4] Identification of bioactive peptides released from in vitro gastrointestinal digestion of yam proteins (Dioscorea cayennensis)
    do Nascimento, Edilza Silva
    Anaya, Katya
    de Oliveira, Julia Mariano Caju
    de Lacerda, Jose Thalles Jocelino Gomes
    Miller, Michael Edward
    Dias, Meriellen
    Mendes, Maria Anita
    Pallone, Juliana de Azevedo Lima
    Arns, Clarice Weis
    Juliano, Maria Aparecida
    Gadelha, Tatiane Santi
    Pacheco, Maria Teresa Bertoldo
    Gadelha, Carlos Alberto de Almeida
    FOOD RESEARCH INTERNATIONAL, 2021, 143
  • [5] Amaranthus hypochondriacus In Vitro Culture for the Production of Bioactive Sustances
    Guadarrama, B.
    Rodriguez, M.
    Perez, C.
    Vernon, J.
    Cruz, F.
    IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2013, 49 : S59 - S60
  • [6] Bioactive peptides released from in vitro digestion of human milk with or without pasteurization
    Wada, Yasuaki
    Loennerdal, Bo
    PEDIATRIC RESEARCH, 2015, 77 (04) : 546 - 553
  • [7] Bioactive peptides released from in vitro digestion of human milk with or without pasteurization
    Yasuaki Wada
    Bo Lönnerdal
    Pediatric Research, 2015, 77 : 546 - 553
  • [8] Identification of Bioactive Peptide Sequences from Amaranth (Amaranthus hypochondriacus) Seed Proteins and Their Potential Role in the Prevention of Chronic Diseases
    Montoya-Rodriguez, Alvaro
    Gomez-Favela, Mario A.
    Reyes-Moreno, Cuauhtemoc
    Milan-Carrillo, Jorge
    de Mejia, Elvira Gonzalez
    COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2015, 14 (02): : 139 - 158
  • [9] Amaranthus hypochondriacus seeds as a rich source of cysteine rich bioactive peptides
    Moyer, Tessa B.
    Schug, Wyatt J.
    Hicks, Leslie M.
    FOOD CHEMISTRY, 2022, 377
  • [10] Amaranthus hypochondriacus seeds as a rich source of cysteine rich bioactive peptides
    Moyer, Tessa B.
    Schug, Wyatt J.
    Hicks, Leslie M.
    Food Chemistry, 2022, 377
12345