Distribution of seroprevalence and risk factors for bovine tuberculosis in east Algeria

Despite the difficulties and the absence of credible scientific information concerning bovine tuberculosis in Algeria, our cross-sectional and inferential study, which is estimated to be a first in Algeria, affected three major semi-intensive regions in East of Algeria, by analyzing 21 holdings which grouped 516 cattle in an intensive and semi-intensive breeding character over a period of 12 months, in order to estimate the seroprevalence and the risk factors those influence the emergence of the disease in these regions. A serological test (ELISA) was carried out on all collected sera, after a stratified two-level sampling. A generalized linear mixed model was used to identify risk factors associated with animal-level positivity. A multivariate descriptive analysis (MCA) was used to identify farm clusters associated with bTB seroprevalence. The results obtained allow us to classify Algeria on the epidemiological level in the field of bovine tuberculosis, in an intermediate situation with a seroprevalence rate of 3.49 % (95 % CI : 1,91, 507); between industrialized countries where the seroprevalence is mostly very low below 0,1% and developing countries with very high seroprevalence such as African-Asian countries. This intermediate epidemiological position is influenced by certain risk factors that are integrated into the three mechanisms commonly known by the scientific community: "contamination by the introduction of an animal"; "neighborhood contamination"; "recurrence". But what characterizes this study is the obtaining of a "Animals purchased from a country listed as not OTF" factor that has returned as a highly protective factor and contributed to the decrease in this seroprevalence, and put Algeria in an intermediate epidemiological situation according to our study, and this is due to a purchase channeled by the state which is exclusive of the countries certified OTF by the OIE.