Evaluation of bacterial cellulose/hyaluronan nanocomposite biomaterials

被引：45
作者：
Li, Ying [1 ,2 ]
Qing, Shuang [1 ]
Zhou, Jianhai [1 ,2 ]
Yang, Guang [1 ,2 ]
机构：
[1] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Dept Biomed Engn, Wuhan 430074, Peoples R China
[2] Huazhong Univ Sci & Technol, Natl Engn Res Ctr Nanomed, Wuhan 430074, Peoples R China
来源：
CARBOHYDRATE POLYMERS | 2014年 / 103卷
基金：
中国国家自然科学基金;
关键词：
Bacterial cellulose; Hyaluronan; Nanocomposites; Wound dressing; HYALURONIC-ACID; MICROBIAL CELLULOSE; HUMAN KERATINOCYTES; MEMBRANES; GRAFTS;
D O I：
10.1016/j.carbpol.2013.12.059
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Bacterial cellulose (BC) is useful in the biomedical field because of its unique structure and properties. The high nano-porosity of BC allows other materials to be incorporated and form reinforced composites. Here we describe the preparation and characterization of novel BC/hyaluronan (HA) nanocomposites with a 3-D network structure. BC/HA was obtained using a solution impregnation method. Elemental and ATR-FTIR analyses showed that this method is highly effective to form composites with BC. Weight loss analysis showed that BC/HA have a lower water loss than BC at 37 degrees C. The total surface area and pore volume of BC/HA films gradually decreased with the HA content, as followed by FE-SEM analysis. The elongation at break of BC/HA films gradually increased as the HA content increased. Thermogravimetric analysis showed that the weight loss for the BC/HA composites were lower than for pure BC between 250 and 350 C. The results of weight loss, elongation at break and thermal stability suggested that these novel BC/HA films could be applied potentially as wound dressing materials. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：496 / 501
页数：6
相关论文
共 34 条
[1]  
Altmann B, 2013, TISSUE ENG PART C-ME, V19, P850, DOI [10.1089/ten.tec.2012.0695, 10.1089/ten.TEC.2012.0695]
[2]   Advantages of hyaluronic acid as a component of fibrin sheet for care of acute wound [J].
Anilkumar, T. V. ;
Muhamed, Jaseer ;
Jose, Anumol ;
Jyothi, Arun ;
Mohanan, P. V. ;
Krishnan, Lissy K. .
BIOLOGICALS, 2011, 39 (02) :81-88
[3]   Bacterial cellulose/silica nanocomposites: Preparation and characterization [J].
Ashori, Alireza ;
Sheykhnazari, Somayeh ;
Tabarsa, Taghi ;
Shakeri, Alireza ;
Golalipour, Masood .
CARBOHYDRATE POLYMERS, 2012, 90 (01) :413-418
[4]   Influence of cultivation conditions on mechanical and morphological properties of bacterial cellulose tubes [J].
Bodin, Aase ;
Backdahl, Henrik ;
Fink, Helen ;
Gustafsson, Lena ;
Risberg, Bo ;
Gatenholm, Paul .
BIOTECHNOLOGY AND BIOENGINEERING, 2007, 97 (02) :425-434
[5]  
Brackmann C, 2012, TISSUE ENG PART C-ME, V18, P227, DOI [10.1089/ten.tec.2011.0211, 10.1089/ten.TEC.2011.0211]
[6]   Electrospinning of hyaluronic acid nanofibers from aqueous ammonium solutions [J].
Brenner, Eric K. ;
Schiffman, Jessica D. ;
Thompson, Ebony A. ;
Toth, Laura J. ;
Schauer, Caroline L. .
CARBOHYDRATE POLYMERS, 2012, 87 (01) :926-929
[7]   Electrospun Ginsenoside Rg3/poly(lactic-co-glycolic acid) fibers coated with hyaluronic acid for repairing and inhibiting hypertrophic scars [J].
Cheng, Liying ;
Sun, Xiaoming ;
Li, Bin ;
Hu, Changmin ;
Yang, Huilin ;
Zhang, Yuguang ;
Cui, Wenguo .
JOURNAL OF MATERIALS CHEMISTRY B, 2013, 1 (35) :4428-4437
[8]   Characterization and biocompatibility of bacterial cellulose/alginate composite sponges with human keratinocytes and gingival fibroblasts [J].
Chiaoprakobkij, Nadda ;
Sanchavanakit, Neeracha ;
Subbalekha, Keskanya ;
Pavasant, Prasit ;
Phisalaphong, Muenduen .
CARBOHYDRATE POLYMERS, 2011, 85 (03) :548-553
[9]  
Ciechanska D, 2004, FIBRES TEXT EAST EUR, V12, P69
[10]   Microbial cellulose - the natural power to heal wounds [J].
Czaja, W ;
Krystynowicz, A ;
Bielecki, S ;
Brown, RM .
BIOMATERIALS, 2006, 27 (02) :145-151
1234