Silver-Catalyzed Radical Tandem Cyclization for the Synthesis of 3,4-Disubstituted Dihydroquinolin-2(1H)-ones

被引：116

作者：

Mai, Wen-Peng ^{[1
]}

Wang, Ji-Tao ^{[1
]}

Yang, Liang-Ru ^{[1
]}

Yuan, Jin-Wei ^{[1
]}

Xiao, Yong-Mei ^{[1
]}

Mao, Pu ^{[1
]}

Qu, Ling-Bo ^{[1
]}

机构：

[1] Henan Univ Technol, Chem & Chem Engn Sch, Zhengzhou 450001, Henan, Peoples R China

来源：

ORGANIC LETTERS | 2014年 / 16卷 / 01期

关键词：

PLATELET AGGREGATION INHIBITORS; ALIPHATIC CARBOXYLIC-ACIDS; METAL-FREE SYNTHESIS; ACTIVATED ALKENES; 2-OXOQUINOLINE DERIVATIVES; OXIDATIVE TRIFLUOROMETHYLATION; H FUNCTIONALIZATION; OXINDOLE SYNTHESIS; ALPHA-ARYLATION; BOND;

D O I：

10.1021/ol403196h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A silver-catalyzed tandem decarboxylative radical addition/cyclization of N-arylcinnamamides with aliphatic carboxylic acids is reported. This method affords a novel and straightforward route to various 3,4-disubstituted dihydroquinolin-2(1H)-ones in aqueous solution.

引用

页码：204 / 207

页数：4

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