The role of vascular endothelial growth factor in neurogenesis in adult brain

被引:18
|
作者
Galvan, Veronica [1 ]
Greenberg, David A. [1 ]
Jin, Kunlin [1 ]
机构
[1] Buck Inst Age Res, Novato, CA 94945 USA
关键词
VEGF; VEGF receptor; neural stem cells; brain; neurogenesis; angiogenesis; growth factor; endothelial cells;
D O I
10.2174/138955706777435742
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
VEGF is a canonical angiogenic factor. In addition, its role as a stimulator of neurogenesis was recently uncovered. Vascular and nervous networks share common molecular mechanisms underlying their morphogenesis. VEGF is likely to regulate both processes during development and in adult organisms.
引用
收藏
页码:667 / 669
页数:3
相关论文
共 50 条
  • [1] Vascular endothelial growth factor induces neurogenesis in the adult brain
    Schänzer, A
    Acker, T
    Cooper-Kuhn, C
    Beck, H
    Plate, KH
    Kuhn, HG
    ACTA NEUROPATHOLOGICA, 2002, 104 (05) : 568 - 568
  • [2] Vascular endothelial growth factor induces neurogenesis in the adult brain
    Schaenzer, A.
    Wachs, F. P.
    Acker, T. S.
    Wilhelm, D.
    Kuhn, H. G.
    Plate, K. H.
    ACTA NEUROPATHOLOGICA, 2006, 112 (03) : 367 - 368
  • [3] Role of vascular endothelial growth factor in adult hippocampal neurogenesis: Implications for the pathophysiology and treatment of depression
    Fournier, Neil M.
    Duman, Ronald S.
    BEHAVIOURAL BRAIN RESEARCH, 2012, 227 (02) : 440 - 449
  • [4] Vascular endothelial growth factor, neurogenesis, and antidepressants
    不详
    NEUROSCIENTIST, 2007, 13 (05): : 415 - 415
  • [5] Vascular endothelial growth factor increases neurogenesis after traumatic brain injury
    Thau-Zuchman, Orli
    Shohami, Esther
    Alexandrovich, Alexander G.
    Leker, Ronen R.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2010, 30 (05): : 1008 - 1016
  • [6] Vascular Abnormalities and the Role of Vascular Endothelial Growth Factor in the Epileptic Brain
    Ogaki, Ari
    Ikegaya, Yuji
    Koyama, Ryuta
    FRONTIERS IN PHARMACOLOGY, 2020, 11
  • [7] Role of vascular endothelial growth factor and vascular endothelial growth factor receptors in vascular development
    Carmeliet, P
    Collen, D
    VASCULAR GROWTH FACTORS AND ANGIOGENESIS, 1999, 237 : 133 - 158
  • [8] The role of vascular endothelial growth factor and vascular endothelial growth inhibitor in clinical outcome of traumatic brain injury
    Li, Min
    Jia, Qiang
    Chen, Tongheng
    Zhao, Zilong
    Chen, Jieli
    Zhang, Jianning
    CLINICAL NEUROLOGY AND NEUROSURGERY, 2016, 144 : 7 - 13
  • [9] Repair following brain trauma: Role of vascular endothelial growth factor
    Nag, S
    Takahashi, JL
    Kilty, DW
    LABORATORY INVESTIGATION, 1997, 76 (01) : 884 - 884
  • [10] Vascular endothelial growth factor localization in the adult
    Maharaj, ASR
    Saint-Geniez, M
    Maldonado, AE
    D'Amore, PA
    AMERICAN JOURNAL OF PATHOLOGY, 2006, 168 (02): : 639 - 648