Monodisperse and Fast-Responsive Poly(N-isopropylacrylamide) Microgels with Open-Celled Porous Structure

被引：47

作者：

Mou, Chuan-Lin ^{[1
]}

Ju, Xiao-Jie ^{[1
]}

Zhang, Lei ^{[1
]}

Xie, Rui ^{[1
]}

Wang, Wei ^{[1
]}

Deng, Nan-Nan ^{[1
]}

Wei, Jie ^{[1
]}

Chen, Qianming ^{[2
]}

Chu, Liang-Yin ^{[1
,3
,4
]}

机构：

[1] Sichuan Univ, Sch Chem Engn, Chengdu 610065, Sichuan, Peoples R China

[2] Sichuan Univ, State Key Lab Oral Dis, Chengdu 610041, Sichuan, Peoples R China

[3] Sichuan Univ, State Key Lab Polymer Mat Engn, Chengdu 610065, Sichuan, Peoples R China

[4] Sichuan Univ, Collaborat Innovat Ctr Biomat Sci & Technol, Chengdu 610065, Sichuan, Peoples R China

来源：

LANGMUIR | 2014年 / 30卷 / 05期

基金：

中国国家自然科学基金;

关键词：

VOLUME-PHASE-TRANSITION; HYDROGELS; TEMPERATURE; FABRICATION; KINETICS; GEL;

D O I：

10.1021/la4046379

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and efficient method is developed to fabricate monodisperse and fast-responsive poly(N-isopropylacrylamide) (PNIPAM) microgels with open-celled porous structure. First, numerous fine oil droplets are fabricated by homogeneous emulsification method and are then evenly dispersed inside monodisperse PNIPAM microgels as porogens via the combination of microfluidic emulsification and UV-initiated polymerization methods. Subsequently, the embedded fine oil droplets inside the PNIPAM microgels are squeezed out upon stimuli-induced rapid volume shrinkage of the microgels; as a result, a spongelike open-celled porous structure is formed inside the PNIPAM microgels. The open-celled porous structure provides numerous interconnected free channels for the water transferring convectively inward or outward during the volume phase transition process of PNIPAM microgels; therefore, the response rates of the PNIPAM microgels with open-celled porous structure are much faster than that of the normal ones in both thermo-responsive shrinking and swelling processes. Because of the fast-responsive characteristics, the microgels with open-celled porous structure will provide ever better performances in their myriad applications, such as microsensors, microactuators, microvalves, and so on.

引用

页码：1455 / 1464

页数：10

共 45 条

[11] Microfluidic synthesis of tunable poly-(N-isopropylacrylamide) microparticles via PEG adjustment [J].

Huang, Shuqiang ;

Lin, Bingcheng ;

Qin, Jianhua .

ELECTROPHORESIS, 2011, 32 (23) :3364-3370

[12] Effects of internal microstructures of poly(N-isopropylacrylamide) hydrogels on thermo-responsive volume phase-transition and controlled-release characteristics [J].

Ju, Xiao-Jie ;

Chu, Liang-Yin ;

Zhu, Xiao-Li ;

Hu, Lin ;

Song, Hang ;

Chen, Wen-Mei .

SMART MATERIALS & STRUCTURES, 2006, 15 (06) :1767-1774

[13] Rapid deswelling response of poly(N-isopropylacrylamide) hydrogels by the formation of water release channels using poly(ethylene oxide) graft chains [J].

Kaneko, Y ;

Nakamura, S ;

Sakai, K ;

Aoyagi, T ;

Kikuchi, A ;

Sakurai, Y ;

Okano, T .

MACROMOLECULES, 1998, 31 (18) :6099-6105

[14] INFLUENCE OF FREELY MOBILE GRAFTED CHAIN-LENGTH ON DYNAMIC PROPERTIES OF COMB-TYPE GRAFTED POLY(N-ISOPROPYLACRYLAMIDE) HYDROGELS [J].

KANEKO, Y ;

SAKAI, K ;

KIKUCHI, A ;

YOSHIDA, R ;

SAKURAI, Y ;

OKANO, T .

MACROMOLECULES, 1995, 28 (23) :7717-7723

[15] TEMPERATURE-RESPONSIVE SHRINKING KINETICS OF POLY(N-ISOPROPYLACRYLAMIDE) COPOLYMER GELS WITH HYDROPHILIC AND HYDROPHOBIC COMONOMERS [J].

KANEKO, Y ;

YOSHIDA, R ;

SAKAI, K ;

SAKURAI, Y ;

OKANO, T .

JOURNAL OF MEMBRANE SCIENCE, 1995, 101 (1-2) :13-22

[16] Fabrication of monodisperse gel shells and functional microgels in microfluidic devices [J].

Kim, Jin-Woong ;

Utada, Andrew S. ;

Fernandez-Nieves, Alberto ;

Hu, Zhibing ;

Weitz, David A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (11) :1819-1822

[17] A simple method to fabricate fluorescent glucose sensor based on dye-complexed microgels [J].

Li, Yingyu ;

Zhou, Shuiqin .

SENSORS AND ACTUATORS B-CHEMICAL, 2013, 177 :792-799

[18] Drying methods affecting the particle sizes, phase transition, deswelling/reswelling processes and morphology of poly(N-isopropylacrylamide) microgel beads [J].

Lin, SY ;

Chen, KS ;

Run-Chu, L .

POLYMER, 1999, 40 (23) :6307-6312

[19] Conversion of Alcoholic Concentration Variations into Mechanical Force via Core-Shell Capsules [J].

Liu, Li ;

Song, Xiao-Lu ;

Ju, Xiao-Jie ;

Xie, Rui ;

Liu, Zhuang ;

Chu, Liang-Yin .

JOURNAL OF PHYSICAL CHEMISTRY B, 2012, 116 (03) :974-979

[20] Smart thermo-triggered squirting capsules for nanoparticle delivery [J].

Liu, Li ;

Wang, Wei ;

Ju, Xiao-Jie ;

Xie, Rui ;

Chu, Liang-Yin .

SOFT MATTER, 2010, 6 (16) :3759-3763

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