MOLECULAR AND SEROLOGICAL PROSPECTS FOR SARS-COV2 EPIDEMIOLOGY

被引:0
作者
Anca, Botezatu [1 ]
Iulia, Iancu, V [1 ]
Adriana, Plesa [1 ]
Irina, Huica [1 ]
Alina, Fudulu [1 ]
Adrian, Albulescu [1 ]
Gabriela, Anton [1 ]
机构
[1] Romanian Acad, Inst Virol Stefan S Nicolau, Dept Mol Virol, Bucharest, Romania
来源
PHARMACOPHORE | 2020年 / 11卷 / 06期
关键词
SARS-CoV-2; pandemic; Covid-19; diagnosis; SARS-CoV2; RT-PCR; CORONAVIRUS; ANTIBODIES; MICROARRAY; OUTBREAK;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The sudden outbreak of the 2019 novel coronavirus "Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, has affected the healthcare system and economy by its rapidly worldwide spreading. The present review intends to describe some of the current molecular and immunological assays used in SARS-CoV-2 detection from an epidemiological perspective, highlighting the importance of rapid test development and improvement. In this purpose the database as Databases (NCBI/PubMed, medRxiv) were used for searching, identifying and synthesizing data regarding SARS-CoV2 diagnosis.This report presents the optimal assays that can discriminate between different stages of the infection pointing out their utility in diagnosis, treatment, and vaccine development. Taken into account SARS-CoV-2 pandemic evolution and the dynamic character of COVID-19 diagnostic assays, the development of a joint effort by the scientific community is necessary for identifying future diagnostic directions that might help the disease management.
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收藏
页码:122 / 131
页数:10
相关论文
共 61 条
[1]  
Albureikan MO, 2020, INT J PHARM PHYTOPHA, V10, P139
[2]  
[Anonymous], 2020, CORONAVIRUS COVID 19
[3]  
[Anonymous], EUA AUTH SER TEST PE
[4]  
[Anonymous], 2020, RAPID HTA ALTERNATIV
[5]  
Arnaout Ramy, 2020, bioRxiv, DOI 10.1101/2020.06.02.131144
[6]   Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response [J].
Astuti, Indwiani ;
Ysrafil .
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS, 2020, 14 (04) :407-412
[7]  
Bulcha B., 2017, J. Biol. Agric. Healthc, V7, P41
[8]   THE TIME COURSE OF THE IMMUNE-RESPONSE TO EXPERIMENTAL CORONAVIRUS INFECTION OF MAN [J].
CALLOW, KA ;
PARRY, HF ;
SERGEANT, M ;
TYRRELL, DAJ .
EPIDEMIOLOGY AND INFECTION, 1990, 105 (02) :435-446
[9]  
Campbell J E, 2004, U.S. Patent Application, Patent No. [10/208,560, 10208560]
[10]   Disappearance of antibodies to SARS-associated coronavirus after recovery [J].
Cao, Wu-Chun ;
Liu, Wei ;
Zhang, Pan-He ;
Zhang, Fang ;
Richardus, Jan H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (11) :1162-1163