Fe-Catalysed oxidative C-H/N-H coupling between aldehydes and simple amides

被引：69

作者：

Wang, Jing ^{[1
]}

Liu, Chao ^{[1
]}

Yuan, Jiwen ^{[1
]}

Lei, Aiwen ^{[1
,2
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China

[2] Jiangxi Normal Univ, Natl Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 36期

基金：

高等学校博士学科点专项科研基金; 中国国家自然科学基金;

关键词：

EFFICIENT SYNTHESIS; BOND FORMATION; AMIDATION; AMINATION; FUNCTIONALIZATION; ARYLATION; ALKENES; REGIOSELECTIVITY; RUTHENIUM; ADJACENT;

D O I：

10.1039/c4cc01447b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel oxidative coupling of aldehydes with simple amides, most likely involving a radical process, was achieved through the use of an iron catalyst. Various amides were utilized as substrates to easily construct imides by coupling with aldehydes. A catalytic cycle involving the benzoyl halide intermediate is proposed based on our experimental results.

引用

页码：4736 / 4739

页数：4

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