Advances in autosomal dominant polycystic kidney disease-2014 and beyond

被引：5

作者：

Braun, William E. ^{[1
,2
]}

机构：

[1] Cleveland Clin, Glickman Urol & Kidney Inst, Dept Hypertens & Nephrol, Cleveland, OH USA

[2] Seven US Ctr, HALT PKD Collaborat Study, Crystal River, FL USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2014年 / 81卷 / 09期

关键词：

INTRACRANIAL ANEURYSMS; RENAL-TRANSPLANTATION; SOMATIC MUTATION; CYST GROWTH; PROGRESSION; INHIBITION; VOLUME; WATER; PKD1; GENE;

D O I：

10.3949/ccjm.81gr.14001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Autosomal dominant polycystic kidney disease (ADPKD), which frequently leads to end-stage renal disease, currently has no specific drug therapies. Better understanding of its pathogenesis and recent clinical trials have led to more accurate diagnosis of the disease and its manifestations, as well as to promising new approaches to treatment.

引用

页码：544 / 555

页数：12

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