The effect of a peripheral mononeuropathy on immunoreactive (ir)-galanin release in the spinal cord of the rat

被引：46
作者：
Colvin, LA [1 ]
Mark, MA [1 ]
Duggan, AW [1 ]
机构：
[1] UNIV EDINBURGH, ROYAL DICK SCH VET STUDIES, DEPT PRECLIN VET SCI, EDINBURGH EH9 1QH, MIDLOTHIAN, SCOTLAND
来源：
BRAIN RESEARCH | 1997年 / 766卷 / 1-2期
基金：
英国惠康基金;
关键词：
chronic constriction injury; dorsal horn; galanin; antibody microprobe; spontaneous release;
D O I：
10.1016/S0006-8993(97)00700-2
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The pattern of ir-galanin release in the spinal cord of rats with a peripheral mononeuropathy was studied. On the side of the cord ipsilateral to the nerve injury enhanced ir-galanin release was found in the superficial dorsal horn. It is probable that, after nerve injury, some primary afferent neurons spontaneously release galanin from their central terminals. (C) 1997 Elsevier Science B.V.
引用
收藏
页码：259 / 261
页数：3
相关论文
共 24 条
  • [1] A PERIPHERAL MONONEUROPATHY IN RAT THAT PRODUCES DISORDERS OF PAIN SENSATION LIKE THOSE SEEN IN MAN
    BENNETT, GJ
    XIE, YK
    [J]. PAIN, 1988, 33 (01) : 87 - 107
  • [2] THE PREPARATION AND USE OF ANTIBODY MICROPROBES
    DUGGAN, AW
    HENDRY, IA
    GREEN, JL
    MORTON, CR
    HUTCHISON, WD
    [J]. JOURNAL OF NEUROSCIENCE METHODS, 1988, 23 (03) : 241 - 247
  • [3] DUGGAN AW, 1991, MONITORING NEURONAL, P181
  • [4] ANALYSIS OF ANTIBODY MICROPROBE AUTORADIOGRAPHS BY COMPUTERIZED IMAGE-PROCESSING
    HENDRY, IA
    MORTON, CR
    DUGGAN, AW
    [J]. JOURNAL OF NEUROSCIENCE METHODS, 1988, 23 (03) : 249 - 256
  • [5] MESSENGER PLASTICITY IN PRIMARY SENSORY NEURONS FOLLOWING AXOTOMY AND ITS FUNCTIONAL IMPLICATIONS
    HOKFELT, T
    ZHANG, X
    WIESENFELDHALLIN, Z
    [J]. TRENDS IN NEUROSCIENCES, 1994, 17 (01) : 22 - 30
  • [6] RELEASE OF IMMUNOREACTIVE GALANIN IN THE SPINAL-CORD OF RATS WITH ANKLE INFLAMMATION - STUDIES WITH ANTIBODY MICROPROBES
    HOPE, PJ
    LANG, CW
    GRUBB, BD
    DUGGAN, AW
    [J]. NEUROSCIENCE, 1994, 60 (03) : 801 - 807
  • [7] SPONTANEOUS DISCHARGE ORIGINATES IN THE DORSAL-ROOT GANGLION AT THE ONSET OF A PAINFUL PERIPHERAL NEUROPATHY IN THE RAT
    KAJANDER, KC
    WAKISAKA, S
    BENNETT, GJ
    [J]. NEUROSCIENCE LETTERS, 1992, 138 (02) : 225 - 228
  • [8] INTRATHECAL INJECTIONS OF GALANIN AND ITS ANTISERUM AFFECT NOCICEPTIVE RESPONSE OF RAT TO MECHANICAL, BUT NOT THERMAL, STIMULI
    KURAISHI, Y
    KAWAMURA, M
    YAMAGUCHI, T
    HOUTANI, T
    KAWABATA, S
    FUTAKI, S
    FUJII, N
    SATOH, M
    [J]. PAIN, 1991, 44 (03) : 321 - 324
  • [9] Mark MA, 1996, J PHYSIOL-LONDON, V495P, pP21
  • [10] DEVELOPMENT OF SPONTANEOUS ACTIVITY AND MECHANOSENSITIVITY IN AXOTOMIZED AFFERENT NERVE-FIBERS DURING THE FIRST HOURS AFTER NERVE TRANSECTION IN RATS
    MICHAELIS, M
    BLENK, KH
    JANIG, W
    VOGEL, C
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 1995, 74 (03) : 1020 - 1027
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