Regulation and enhancement of lipid accumulation in oil crops: The use of metabolic control analysis for informed genetic manipulation

被引:26
作者
Harwood, John L. [1 ]
Ramli, Umi S. [1 ]
Tang, Mingguo [1 ]
Quant, Patti A. [2 ]
Weselake, Randall J. [3 ]
Fawcett, Tony [4 ]
Guschina, Irina A. [1 ]
机构
[1] Cardiff Univ, Sch Biosci, Cardiff CF10 3AX, S Glam, Wales
[2] Univ Oxford, Dept Biochem, Oxford OX1 3QU, England
[3] Univ Alberta, Dept Agr Food & Nutr Sci, Edmonton, AB, Canada
[4] Univ Durham, Dept Biol Sci, Durham, England
基金
英国生物技术与生命科学研究理事会; 加拿大自然科学与工程研究理事会;
关键词
Metabolic control analysis; Oil crops; Regulation of oil accumulation; TAG synthesis; RAPE BRASSICA-NAPUS; FATTY-ACID-COMPOSITION; DIACYLGLYCEROL ACYLTRANSFERASE; OVER-EXPRESSION; TRIACYLGLYCEROL SYNTHESIS; CAMELINA-SATIVA; FLUX CONTROL; BIOSYNTHESIS; ARABIDOPSIS; L;
D O I
10.1002/ejlt.201300257
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Plant oils are a very valuable agricultural commodity. They are currently mainly used (>80%) for food and animal feed but, increasingly, they have utility as renewable sources of industrial feedstocks or biofuel. Because of finite agricultural land, the best way to increase availability (in order to match demand) is by improving productivity. To do this requires a knowledge of metabolism and its regulation. Various methods have been used to provide information but only systems biology can yield quantitative data about complete metabolic pathways. We have used metabolic control analysis to provide information about major oil crops such as oilseed rape, oil palm, olive, and soybean. Such knowledge has then been used to inform genetic manipulation for crop improvement.
引用
收藏
页码:1239 / 1246
页数:8
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