Harm to the liver among employees of the Municipal Police Force

被引:8
作者
Tomao, E
Baccolo, TP
Sacchi, L
De Sio, S
Tomei, F
机构
[1] Univ Roma La Sapienza, Dept Occupat Med, I-00161 Rome, Italy
[2] ITAF, IML, Ctr Aeromed Evaluat & Occupat Med, Rome, Italy
关键词
Municipal Police; urban pollution; hepatotoxicity; mixtures of solvents;
D O I
10.1080/09603120220129300
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The purpose of the study is to assess whether employees of the Municipal Police Force of a big city exposed to urban pollution are at risk of hepatotoxicity. The usual clinical practice tests like AST, ALT, gamma-GT, AP, conjugated and total bilirubin were carried out, accompanied by a questionnaire designed to identify the possible risk factors and the principal non-professional confounding factors for hepatotoxicity. The study covered 118 male Municipal Police employees performing traffic duties and 118 male blood donors engaged in office work. There were significant differences between exposed and controls with regard to the average AST and ALT values and values above the normal laboratory range; this was also the case for the distribution. The results suggest that there may be the possibility of liver damage among asymptomatic members of the Municipal Police Force and that periodic hepatic screening, with the above-mentioned tests, could be useful. It is presumed that chemical agents present in urban air in big cities may cause damage to the liver, even at exposure levels that fluctuate around the admissible environmental concentrations.
引用
收藏
页码:145 / 151
页数:7
相关论文
共 24 条
[1]  
Boari C, 1985, Minerva Med, V76, P1055
[2]  
CHEN JD, 1991, BRIT J IND MED, V48, P696
[3]   Urban benzene and population exposure [J].
Cocheo, V ;
Sacco, P ;
Boaretto, C ;
De Saeger, E ;
Ballesta, PP ;
Skov, H ;
Goelen, E ;
Gonzalez, N ;
Caracena, AB .
NATURE, 2000, 404 (6774) :141-142
[4]   Exposure to benzene in urban workers: environmental and biological monitoring of traffic police in Rome [J].
Crebelli, R ;
Tomei, F ;
Zijno, A ;
Ghittori, S ;
Imbriani, M ;
Gamberale, D ;
Martini, A ;
Carere, A .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2001, 58 (03) :165-171
[5]  
*DIP POL AMB AGR C, 2001, PREV INQ ATM
[6]  
DOOSSING M, 1985, OCCUP ENV HLTH, V56, P1
[7]   SERUM BILE-ACID CONCENTRATIONS AS A LIVER-FUNCTION TEST IN WORKERS OCCUPATIONALLY EXPOSED TO ORGANIC-SOLVENTS [J].
FRANCO, G ;
FONTE, R ;
TEMPINI, G ;
CANDURA, F .
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 1986, 58 (02) :157-164
[8]   Cancer mortality among shoe manufacturing workers: An analysis of two cohorts [J].
Fu, H ;
Demers, PA ;
Costantini, AS ;
Winter, P ;
Colin, D ;
Kogevinas, M ;
Boffetta, P .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1996, 53 (06) :394-398
[9]   LIVER STRUCTURE AND FUNCTION IN PRINT WORKERS EXPOSED TO TOLUENE [J].
GUZELIAN, P ;
MILLS, S ;
FALLON, HJ .
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1988, 30 (10) :791-796
[10]   INFLUENCE OF SMOKING ON CAFFEINE ELIMINATION IN HEALTHY-VOLUNTEERS AND IN PATIENTS WITH ALCOHOLIC LIVER-CIRRHOSIS [J].
JOERES, R ;
KLINKER, H ;
HEUSLER, H ;
EPPING, J ;
ZILLY, W ;
RICHTER, E .
HEPATOLOGY, 1988, 8 (03) :575-579