Risk factors for mortality and hospital re-admission after surgical ventricular restoration

被引:33
作者
Sartipy, Ulrik [1 ]
Albage, Anders
Lindblom, Dan
机构
[1] Karolinska Univ Hosp, Dept Cardiothorac Surg & Anesthesiol, SE-17176 Stockholm, Sweden
[2] Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden
关键词
left ventricular reconstruction; surgical ventricular restoration; Dor procedure; heart failure surgery; coronary artery disease;
D O I
10.1016/j.ejcts.2006.08.020
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Surgical ventricutar restoration is an option in patients with coronary artery disease, heart failure, postinfarction left ventricular aneurysm or ischemic dilated cardiomyopathy with or without ventricutar tachycardia. The aims of this study were to investigate survival and readmission for heart failure and to identify predictors for early and long-term mortality and re-admission after surgical ventricular restoration. Methods: Pre- and postoperative data were collected for 136 consecutive patients who underwent surgical ventricutar restoration for postinfarction left ventricular aneurysm or ischemic dilated cardiomyopathy during 1994-2005. Survival and risk factors for mortality and hospital re-admission were analyzed by using multivariable models. Results: Early mortality was 10/136 (7.4%). At 1, 3, 5 and 9 years overall actuarial survival was 89%, 80%, 68% and 62%. Increasing age, diabetes and mitral regurgitation grade III-IV were associated with an increased risk for late mortality. Freedom from re-hospitalization due to heart failure or cardiac death in operative survivors at 1, 3 and 5 years was 78%, 72% and 58%. Risk factors for re-hospitatization or cardiac death in operative survivors were increasing age and increasing grade of mitral regurgitation. Conclusions: Surgical ventricutar restoration by the Dor procedure can achieve good tong-term survival and a high degree of freedom from readmission for heart failure in patients with advanced ischemic heart disease. We found a strong association between increasing grade of mitral regurgitation and both long-term mortality and re-admission for heart failure. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:762 / 769
页数:8
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