Cadmium-containing quantum dots: properties, applications, and toxicity

被引:110
作者
Mo, Dan [1 ,2 ]
Hu, Liang [1 ,2 ]
Zeng, Guangming [1 ,2 ]
Chen, Guiqiu [1 ,2 ]
Wan, Jia [1 ,2 ]
Yu, Zhigang [1 ,2 ]
Huang, Zhenzhen [1 ,2 ]
He, Kai [1 ,2 ]
Zhang, Chen [1 ,2 ]
Cheng, Min [1 ,2 ]
机构
[1] Hunan Univ, Coll Environm Sci & Engn, Changsha 410082, Hunan, Peoples R China
[2] Hunan Univ, Minist Educ, Key Lab Environm Biol & Pollut Control, Changsha 410082, Hunan, Peoples R China
基金
中国国家自然科学基金;
关键词
Quantumdots; Fluorescence; Biosensing; Bioimaging; Drug delivery; Toxicity; MESOPOROUS SILICA NANOPARTICLES; PROTEIN-COUPLED RECEPTOR; IN-VIVO DISTRIBUTION; DRUG-DELIVERY; PHANEROCHAETE-CHRYSOSPORIUM; ENERGY-TRANSFER; LIVING CELLS; LONG-TERM; FLUORESCENT NANOCRYSTALS; ULTRASENSITIVE DETECTION;
D O I
10.1007/s00253-017-8140-9
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The marriage of biology with nanomaterials has significantly accelerated advancement of biological techniques, profoundly facilitating practical applications in biomedical fields. With unique optical properties (e.g., tunable broad excitation, narrow emission spectra, robust photostability, and high quantum yield), fluorescent quantum dots (QDs) have been reasonably functionalized with controllable interfaces and extensively used as a new class of optical probe in biological researches. In this review, we summarize the recent progress in synthesis and properties of QDs. Moreover, we provide an overview of the outstanding potential of QDs for biomedical research and innovative methods of drug delivery. Specifically, the applications of QDs as novel fluorescent nanomaterials for biomedical sensing and imaging have been detailedly highlighted and discussed. In addition, recent concerns on potential toxicity of QDs are also introduced, ranging from cell researches to animal models.
引用
收藏
页码:2713 / 2733
页数:21
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