Ovarian cancer is the leading cause of death from gynecological cancer in western countries. The absence of an effective screening program as well as specific symptoms, makes the diagnosis difficult and often made in advanced stages of the disease, in the presence of peritoneal dissemination. The complete cytoreduction of the disease and tumor sensitivity to systemic chemotherapy based on plafinums, are the two main prognostic factors. However in patients with complete cytoreduction the recurrence rate is high. The microscopic component of the disease at the end of the cytoreduction is responsible for these recurrences and the use of intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) in the same time of surgery has been proposed as a reasonable therapeutic option for treatment. However, the absence of sufficient levels of scientific evidence to support the use of HIPEC in patients with ovarian cancer with peritoneal dissemination does not allow a general recommendation outside of clinical trials. The main objective of this study is to identify the strengths and weaknesses of HIPEC treatment in ovarian cancer with peritoneal dissemination, and to know which points can be improved in the future. (C) 2015 Elsevier Inc. All rights reserved.
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Barlin, Joyce N.
Dao, Fanny
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机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Dao, Fanny
Zgheib, Nadim Bou
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h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Zgheib, Nadim Bou
Ferguson, Sarah E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Toronto, Div Gynecol Oncol, Princess Margaret Hosp, Dept Obstet & Gynecol, Toronto, ON, CanadaMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Ferguson, Sarah E.
Sabbatini, Paul J.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Sabbatini, Paul J.
Hensley, Martee L.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Hensley, Martee L.
Bell-McGuinn, Katherine M.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Bell-McGuinn, Katherine M.
Konner, Jason
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Konner, Jason
Tew, William P.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Tew, William P.
Aghajanian, Carol
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Aghajanian, Carol
Chi, Dennis S.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
机构:
Johns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
Johns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Oncol, Baltimore, MD 21205 USAJohns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
Bristow, Robert E.
Palis, Bryan E.
论文数: 0引用数: 0
h-index: 0
机构:
Commiss Canc Amer Coll Surg, Natl Canc Data Base, Chicago, IL USAJohns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
Palis, Bryan E.
Chi, Dennis S.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, New York, NY 10021 USAJohns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
Chi, Dennis S.
Cliby, William A.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Dept Gynecol Surg, Rochester, MN USAJohns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Barlin, Joyce N.
Dao, Fanny
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Dao, Fanny
Zgheib, Nadim Bou
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Zgheib, Nadim Bou
Ferguson, Sarah E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Toronto, Div Gynecol Oncol, Princess Margaret Hosp, Dept Obstet & Gynecol, Toronto, ON, CanadaMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Ferguson, Sarah E.
Sabbatini, Paul J.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Sabbatini, Paul J.
Hensley, Martee L.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Hensley, Martee L.
Bell-McGuinn, Katherine M.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Bell-McGuinn, Katherine M.
Konner, Jason
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Konner, Jason
Tew, William P.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Tew, William P.
Aghajanian, Carol
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol Serv, Dept Med, New York, NY 10065 USA
Weill Cornell Med Coll, New York, NY USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
Aghajanian, Carol
Chi, Dennis S.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, New York, NY 10065 USA
机构:
Johns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
Johns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Oncol, Baltimore, MD 21205 USAJohns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
Bristow, Robert E.
Palis, Bryan E.
论文数: 0引用数: 0
h-index: 0
机构:
Commiss Canc Amer Coll Surg, Natl Canc Data Base, Chicago, IL USAJohns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
Palis, Bryan E.
Chi, Dennis S.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, New York, NY 10021 USAJohns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
Chi, Dennis S.
Cliby, William A.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Dept Gynecol Surg, Rochester, MN USAJohns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Kelly Gynecol Oncol Serv, Dept Gynecol & Obstet, Baltimore, MD 21205 USA