Spinal Cord Epidural Stimulation for Lower Limb Motor Function Recovery in Individuals with Motor Complete Spinal Cord Injury

被引：39

作者：

Rejc, Enrico ^{[1
,2
]}

Angeli, Claudia A. ^{[1
,3
]}

机构：

[1] Univ Louisville, Kentucky Spinal Cord Injury Res Ctr, 220 Abraham Flexner Way, Louisville, KY 40202 USA

[2] Univ Louisville, Dept Neurol Surg, Louisville, KY 40202 USA

[3] KentuckyOne Hlth, Frazier Rehab Inst, 220 Abraham Flexner Way, Louisville, KY 40202 USA

来源：

PHYSICAL MEDICINE AND REHABILITATION CLINICS OF NORTH AMERICA | 2019年 / 30卷 / 02期

关键词：

Spinal cord injury; Epidural stimulation; Activity-based training; Spinal motor learning; Rehabilitation; Neuromodulation; DORSAL-COLUMN STIMULATION; HUMAN LUMBOSACRAL CORD; ELECTRICAL-STIMULATION; POSTERIOR STRUCTURES; LUMBAR CORD; SPATIOTEMPORAL NEUROMODULATION; DEGENERATIVE DISEASES; PLASTICITY; WALKING; LOCOMOTION;

D O I：

10.1016/j.pmr.2018.12.009

中图分类号：

R49 [康复医学];

学科分类号：

100215 ;

摘要：

Spinal cord epidural stimulation (scES) combined with activity-based training can promote lower limb motor function recovery in chronic, motor complete spinal cord-injured individuals. Task-and individual-specific scES parameters modulate the excitability of human spinal circuitry so that sensory information and residual descending input can serve as sources of control for generating motor patterns appropriate for standing, stepping, and volitionally moving the lower limb. Task-specific activity-based training with scES is crucial for promoting neural plasticity and motor function improvement. Future studies with more individuals and advanced stimulation technology are needed to better understand the recovery potential in this population.

引用

页码：337 / +

页数：20

共 50 条

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