Synthesis of Colchicine C-10-Amino-Acid Derivatives

被引：4

作者：

Garazd, Ya. L. ^{[1
]}

Garazd, M. M. ^{[1
]}

Kartsev, V. G. ^{[2
]}

机构：

[1] Eximed, UA-02160 Kiev, Ukraine

[2] InterBioScreen, Moscow 119019, Russia

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2015年 / 51卷 / 06期

关键词：

colchicine; amino-acid derivatives; colchicine C-10-amine derivatives; ANALOGS;

D O I：

10.1007/s10600-015-1510-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Colchicine derivatives modified on C-10 by natural and synthetic amino acids were synthesized.

引用

页码：1138 / 1141

页数：4

共 12 条

[1]

Aitkhozhina NA, 1996, BIOORG KHIM+, V22, P383

[2] Sulfur-containing aminoacid derivatives of cholchicine and cholchamine and derivatives of isothiouronium and mercaptoethylamine [J].

Enikeeva, ZM .

CHEMISTRY OF NATURAL COMPOUNDS, 1999, 35 (05) :556-563

[3] 5 NEW ALKALOIDS FROM COLCHICUM-RITCHII [J].

FREYER, AJ ;

ABUZARGA, MH ;

FIRDOUS, S ;

GUINAUDEAU, H ;

SHAMMA, M .

JOURNAL OF NATURAL PRODUCTS, 1987, 50 (04) :684-689

[4] Synthesis, antiproliferative and antibacterial evaluation of C-ring modified colchicine analogues [J].

Huczynski, Adam ;

Rutkowski, Jacek ;

Popiel, Katarzyna ;

Maj, Ewa ;

Wietrzyk, Joanna ;

Stefanska, Joanna ;

Majcher, Urszula ;

Bartl, Franz .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 90 :296-301

[5]

KISELEV VV, 1961, ZH OBSHCH KHIM+, V31, P334

[6] SYNTHESES OF COLCHICINE AND ISOCOLCHICINE LABELED WITH C-11 OR C-13 [J].

KOTHARI, PJ ;

FINN, RD ;

LARSON, SM .

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1995, 36 (06) :521-528

[7] A CONVENIENT ENTRY TO NEW C-7-MODIFIED COLCHICINOIDS THROUGH AZIDE ALKYNE [3+2] CYCLOADDITION: APPLICATION OF RING-CONTRACTIVE REARRANGEMENTS [J].

Nicolaus, Norman ;

Reball, Jens ;

Sitnikov, Nikolay ;

Velder, Janna ;

Termath, Andreas ;

Fedorov, Alexey Yu. ;

Schmalz, Hans-Guenther .

HETEROCYCLES, 2011, 82 (02) :1585-+

[8]

Popova O. I., 1991, CHEM NAT COM, V27, P647

[9] FLUORINATED COLCHICINOIDS - ANTITUBULIN AND CYTOTOXIC PROPERTIES [J].

RINGEL, I ;

JAFFE, D ;

ALERHAND, S ;

BOYE, O ;

MUZAFFAR, A ;

BROSSI, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (11) :3334-3338

[10]

Semenov A. A., 2009, PRINCIPLES CHEM NATU, V2

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