Light-Triggered Assembly of Gold Nanoparticles for Photothermal Therapy and Photoacoustic Imaging of Tumors In Vivo

被引：520
作者：
Cheng, Xiaju [1 ]
Sun, Rui [1 ]
Yin, Ling [1 ,2 ]
Chai, Zhifang [1 ]
Shi, Haibin [1 ]
Gao, Mingyuan [1 ,3 ]
机构：
[1] Soochow Univ, Ctr Mol Imaging & Nucl Med, Sch Radiol & Interdisciplinary Sci RAD X, Collaborat Innovat Ctr Radiat Med,Jiangsu Higher, Suzhou 215123, Peoples R China
[2] Jining Univ, Dept Chem & Chem Engn, Qufu 273155, Peoples R China
[3] Chinese Acad Sci, Sch Chem & Chem Engn, Univ Chinese Acad Sci, Inst Chem, Beijing 100049, Peoples R China
来源：
ADVANCED MATERIALS | 2017年 / 29卷 / 06期
基金：
中国国家自然科学基金;
关键词：
CELLULAR UPTAKE; AGGREGATION; DNA; ORGANIZATION; UV;
D O I：
10.1002/adma.201604894
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Photocross-linkable Au nanoparticles are prepared through surface decoration of photo-labile diazirine moieties. Both in vitro and in vivo studies indicate that the light-triggered cross-linking can dramatically shift the surface plasmon resonance of Au nanoparticles to near-infrared regions, which in consequence remarkably enhances their efficacy for photothermal therapy and photoacoustic imaging of tumors in vivo.
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页数：6
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共 45 条
  • [1] Recent Advances of Light-Mediated Theranostics
    Ai, Xiangzhao
    Mu, Jing
    Xing, Bengang
    [J]. THERANOSTICS, 2016, 6 (13): : 2439 - 2457
  • [2] Organization of 'nanocrystal molecules' using DNA
    Alivisatos, AP
    Johnsson, KP
    Peng, XG
    Wilson, TE
    Loweth, CJ
    Bruchez, MP
    Schultz, PG
    [J]. NATURE, 1996, 382 (6592) : 609 - 611
  • [3] [Anonymous], 2009, ANGEW CHEM
  • [4] Intrinsic therapeutic applications of noble metal nanoparticles: past, present and future
    Arvizo, Rochelle R.
    Bhattacharyya, Sanjib
    Kudgus, Rachel A.
    Giri, Karuna
    Bhattacharya, Resham
    Mukherjee, Priyabrata
    [J]. CHEMICAL SOCIETY REVIEWS, 2012, 41 (07) : 2943 - 2970
  • [5] Theranostic Nanoshells: From Probe Design to Imaging and Treatment of Cancer
    Bardhan, Rizia
    Lal, Surbhi
    Joshi, Amit
    Halas, Naomi J.
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (10) : 936 - 946
  • [6] Spontaneous Organization of Inorganic Nanoparticles into Nanovesicles Triggered by UV Light
    Bian, Tong
    Shang, Lu
    Yu, Huijun
    Perez, Maria Teresa
    Wu, Li-Zhu
    Tung, Chen-Ho
    Nie, Zhihong
    Tang, Zhiyong
    Zhang, Tierui
    [J]. ADVANCED MATERIALS, 2014, 26 (32) : 5613 - +
  • [7] Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity
    Boisselier, Elodie
    Astruc, Didier
    [J]. CHEMICAL SOCIETY REVIEWS, 2009, 38 (06) : 1759 - 1782
  • [8] Construction and Validation of Nano Gold Tripods for Molecular Imaging of Living Subjects
    Cheng, Kai
    Kothapalli, Sri-Rajasekhar
    Liu, Hongguang
    Koh, Ai Leen
    Jokerst, Jesse V.
    Jiang, Han
    Yang, Meng
    Li, Jinbo
    Levi, Jelena
    Wu, Joseph C.
    Gambhir, Sanjiv S.
    Cheng, Zhen
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (09) : 3560 - 3571
  • [9] Functional Nanomaterials for Phototherapies of Cancer
    Cheng, Liang
    Wang, Chao
    Feng, Liangzhu
    Yang, Kai
    Liu, Zhuang
    [J]. CHEMICAL REVIEWS, 2014, 114 (21) : 10869 - 10939
  • [10] Protein Corona Influences Cellular Uptake of Gold Nanoparticles by Phagocytic and Nonphagocytic Cells in a Size-Dependent Manner
    Cheng, Xiaju
    Tian, Xin
    Wu, Anqing
    Li, Jianxiang
    Tian, Jian
    Chong, Yu
    Chai, Zhifang
    Zhao, Yuliang
    Chen, Chunying
    Ge, Cuicui
    [J]. ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (37) : 20568 - 20575
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