An Automatic Mass Screening System for Cervical Cancer Detection Based on Convolutional Neural Network

被引:8
作者
Rehman, Aziz-ur [1 ]
Ali, Nabeel [2 ]
Taj, Imtiaz A. [2 ]
Sajid, Muhammad [3 ]
Karimov, Khasan S. [1 ,4 ]
机构
[1] GIK Inst Engn Sci & Technol, Dept Elect Engn, Topi 23640, Khyber Pakhtunk, Pakistan
[2] Capital Univ Sci & Technol, Dept Elect Engn, Islamabad Expressway,Kahuta Rd,Zone 5, Islamabad, Pakistan
[3] Mirpur Univ Sci & Technol MUST, Dept Elect Engn, Mirpur 10250, Pakistan
[4] Acad Sci Republ Tajikistan, Ctr Innovat & New Technol, Rudaki Ave 33, Dushanbe 734015, Tajikistan
关键词
PAP-SMEAR IMAGES; CELL-NUCLEI; CLASSIFICATION; CYTOLOGY; SEGMENTATION; PREVENTION; DIAGNOSIS; FRAMEWORK;
D O I
10.1155/2020/4864835
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Cervical cancer is the fourth most common type of cancer and is also a leading cause of mortality among women across the world. Various types of screening tests are used for its diagnosis, but the most popular one is the Papanicolaou smear test, in which cell cytology is carried out. It is a reliable tool for early identification of cervical cancer, but there is always a chance of misdiagnosis because of possible errors in human observations. In this paper, an auto-assisted cervical cancer screening system is proposed that uses a convolutional neural network trained on Cervical Cells database. The training of the network is accomplished through transfer learning, whereby initializing weights are obtained from the training on ImageNet dataset. After fine-tuning the network on the Cervical Cells database, the feature vector is extracted from the last fully connected layer of convolutional neural network. For final classification/screening of the cell samples, three different classifiers are proposed including Softmax regression (SR), Support vector machine (SVM), and GentleBoost ensemble of decision trees (GEDT). The performance of the proposed screening system is evaluated for two different testing protocols, namely, 2-class problem and 7-class problem, on the Herlev database. Classification accuracies of SR, SVM, and GEDT for the 2-class problem are found to be 98.8%, 99.5%, and 99.6%, respectively, while for the 7-class problem, they are 97.21%, 98.12%, and 98.85%, respectively. These results show that the proposed system provides better performance than its previous counterparts under various testing conditions.
引用
收藏
页数:14
相关论文
共 55 条
  • [1] Ampazis N, 2004, LECT NOTES COMPUT SC, V3025, P230
  • [2] [Anonymous], 2017, INT J CONT MED RES
  • [3] Cervical Cancer Detection Using Segmentation on Pap smear Images
    Arya, Mithlesh
    Mittal, Namita
    Singh, Girdhari
    [J]. PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON INFORMATICS AND ANALYTICS (ICIA' 16), 2016,
  • [4] Bak ES, 2004, P ANN INT IEEE EMBS, V26, P1802
  • [5] Bar Y, 2015, I S BIOMED IMAGING, P294, DOI 10.1109/ISBI.2015.7163871
  • [6] Screening for Cervical Cancer Using Automated Analysis of PAP-Smears
    Bengtsson, Ewert
    Malm, Patrik
    [J]. COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE, 2014, 2014
  • [7] Automated screening of cervical cytology specimens
    Birdsong, GG
    [J]. HUMAN PATHOLOGY, 1996, 27 (05) : 468 - 481
  • [8] Automated classification of Pap smear images to detect cervical dysplasia
    Bora, Kangkana
    Chowdhury, Manish
    Mahanta, Lipi B.
    Kundu, Malay Kumar
    Das, Anup Kumar
    [J]. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2017, 138 : 31 - 47
  • [9] Incidence trends of adenocarcinoma of the cervix in 13 European countries
    Bray, F
    Carstensen, B
    Moller, H
    Zappa, M
    Zakelj, MP
    Lawrence, G
    Hakama, M
    Weiderpass, E
    [J]. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2005, 14 (09) : 2191 - 2199
  • [10] Buyssens Pierre, 2013, Computer Vision - ACCV 2012. 11th Asian Conference on Computer Vision. Revised Selected Papers, P342, DOI 10.1007/978-3-642-37444-9_27