Green Synthesis of Luminescent Nitrogen-Doped Carbon Dots from Milk and Its Imaging Application

被引:486
作者
Wang, Li [1 ]
Zhou, H. Susan [1 ]
机构
[1] Worcester Polytech Inst, Dept Chem Engn, Life Sci & Bioengn Ctr, Worcester, MA 01609 USA
基金
美国国家科学基金会;
关键词
ONE-STEP SYNTHESIS; QUANTUM DOTS; FACILE SYNTHESIS; IONS; PHOTOLUMINESCENCE; CHEMILUMINESCENCE; FLUORESCENCE; NANODOTS; JUICE; RICH;
D O I
10.1021/ac502646x
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In the present work, a completely green synthetic method for producing fluorescent nitrogen-doped carbon dots by using milk is introduced. The process is environmentally friendly, simple, and efficient. By hydrothermal heating of milk, we produced monodispersed, highly fluorescent carbon dots with a size of about 3 nm. Imaging of U87 cells, a human brain glioma cancer cell line, can be easily achieved with high resolution using the prepared carbon dots as probes and validates their use in imaging applications.
引用
收藏
页码:8902 / 8905
页数:4
相关论文
共 29 条
[1]   In Situ Building of a Nanoprobe Based on Fluorescent Carbon Dots for Methylmercury Detection [J].
Costas-Mora, Isabel ;
Romero, Vanesa ;
Lavilla, Isela ;
Bendicho, Carlos .
ANALYTICAL CHEMISTRY, 2014, 86 (09) :4536-4543
[2]   A green and facile approach for the synthesis of water soluble fluorescent carbon dots from banana juice [J].
De, Bibekananda ;
Karak, Niranjan .
RSC ADVANCES, 2013, 3 (22) :8286-8290
[3]   New methods of synthesis and varied properties of carbon quantum dots with high nitrogen content [J].
Dey, Sunita ;
Chithaiah, Pallellappa ;
Belawadi, Sunita ;
Biswas, Kanishka ;
Rao, C. N. R. .
JOURNAL OF MATERIALS RESEARCH, 2014, 29 (03) :383-391
[4]   Polyamine-Functionalized Carbon Quantum Dots as Fluorescent Probes for Selective and Sensitive Detection of Copper Ions [J].
Dong, Yongqiang ;
Wang, Ruixue ;
Li, Geli ;
Chen, Congqiang ;
Chi, Yuwu ;
Chen, Guonan .
ANALYTICAL CHEMISTRY, 2012, 84 (14) :6220-6224
[5]   Photoluminescent carbon dots directly derived from polyethylene glycol and their application for cellular imaging [J].
Fan, Rui-Jun ;
Sun, Qiang ;
Zhang, Ling ;
Zhang, Yan ;
Lu, An-Hui .
CARBON, 2014, 71 :87-93
[6]   One step synthesis of C-dots by microwave mediated caramelization of poly(ethylene glycol) [J].
Jaiswal, Amit ;
Ghosh, Siddhartha Sankar ;
Chattopadhyay, Arun .
CHEMICAL COMMUNICATIONS, 2012, 48 (03) :407-409
[7]  
Jia XF, 2012, NANOSCALE, V4, P5572, DOI [10.1039/c2nr31319g, 10.1039/c2ib31319g]
[8]   An absolutely green approach to fabricate carbon nanodots from soya bean grounds [J].
Li, Wenbin ;
Yue, Zhao ;
Wang, Cheng ;
Zhang, Wei ;
Liu, Guohua .
RSC ADVANCES, 2013, 3 (43) :20662-20665
[9]   Easy synthesis of highly fluorescent carbon quantum dots from gelatin and their luminescent properties and applications [J].
Liang, Qinghua ;
Ma, Wangjing ;
Shi, Yao ;
Li, Zhi ;
Yang, Xinming .
CARBON, 2013, 60 :421-428
[10]   Peroxynitrous-Acid-Induced Chemiluminescence of Fluorescent Carbon Dots for Nitrite Sensing [J].
Lin, Zhen ;
Xue, Wei ;
Chen, Hui ;
Lin, Jin-Ming .
ANALYTICAL CHEMISTRY, 2011, 83 (21) :8245-8251