Synthesis and Crystal Structure of 3-{[(1E) 1-(2-Hydroxyphenyl) methylidene]amino}-4-cyanopyrazole

被引：0
|
作者：
Cheng Qing-Fang [1 ,2 ]
Xu Xing-You [1 ,2 ]
Wang Qi-Fa [3 ]
Qian Bao-Hua [2 ]
Liu Wang-Jun [2 ]
Yang Xu-Jie [1 ]
机构：
[1] Nanjing Univ Sci & Technol, Mat Chem Lab, Nanjing 210094, Peoples R China
[2] Huaihai Inst Technol, Dept Chem Technol, Lianyungang 222005, Peoples R China
[3] Huaihai Inst Technol, Jiangsu Key Lab Marine Biotechnol, Lianyungang 222005, Peoples R China
来源：
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY | 2009年 / 28卷 / 10期
关键词：
Schiff base; pyrazole derivative; crystal structure; antibacterial activities; SCHIFF-BASE; S-BENZYLDITHIOCARBAZATE; COMPLEXES;
D O I：
暂无
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The title Schiff base compound (C11H8N4O), a derivative of pyrazole, has been synthesized by the reaction of salicylaldehyde and 3-amino-4-cyanopyrazole in absolute ethanol and characterized by elemental analyses, IR, H-1 NMR and X-ray single-crystal diffraction. The crystal belongs to the monoclinic system, space group P2(1)/n, with a = 7.5594(7), b = 18.3342(19), c = 22.461(2) angstrom, beta = 98.419(2)degrees, V = 3079.5(5) angstrom(3), M-r = 212.21, Z 12, F(000) = 1320, D-c = 1.373 g/cm(3), T = 298(2) K, lambda = 0.71073 angstrom, the final R = 0.0571 and wR 0.0493. A total of 5412 unique reflections were collected, of which 1612 with I > 2 sigma(I) were observed. The molecular structure adopts a trans configuration about the C=N double bond. The preliminary biological tests show that the compound has high antibacterial activities.
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页码：1281 / 1285
页数：5
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