What about TSH and Anti-Thyroid Antibodies in Patients with Autoimmune Thyroiditis and Celiac Disease Using a Gluten-Free Diet? A Systematic Review

被引:10
|
作者
Malandrini, Sabrina [1 ]
Trimboli, Pierpaolo [2 ,3 ]
Guzzaloni, Gabriele [2 ]
Virili, Camilla [4 ]
Lucchini, Barbara [2 ,3 ]
机构
[1] Reg Hosp Locarno, Dept Internal Med, CH-6600 Locarno, Switzerland
[2] Ente Osped Cantonale EOC, Clin Endocrinol, CH-6500 Bellinzona, Switzerland
[3] Univ Svizzera Italiana USI, Fac Biomed Sci, CH-6900 Lugano, Switzerland
[4] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, I-04100 Latina, Italy
关键词
thyroid hormones; thyroid antibodies; celiac disease; gluten-free diet; systematic review; PREVALENCE;
D O I
10.3390/nu14081681
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The prevalence of celiac disease (CD) in patients with chronic autoimmune thyroiditis (CAIT) is estimated to be between 2 and 7.8%. A gluten-free diet (GFD) in patients with CD is suggested to have a beneficial effect on CAIT. Thus, the present systematic review was undertaken to achieve more robust evidence about the change in thyroid stimulating hormone (TSH) and thyroid-specific antibodies (T-Ab) levels obtained in CD patients following a GFD. A specific search strategy was planned. The last search was performed on March 2022. The following data were mainly searched for in order to be extracted: sample size, mean and/or median with standard deviation (SD), and error (SE), individually, of thyroid hormones and T-Ab at baseline and after GFD, and the duration of the study. The initial search retrieved 297 records and 6 articles met the inclusion criteria. In total, 50 patients with both CD and CAIT and 45 controls were reported. The effects of a GFD on the thyroid hormonal and immunological profile could be extracted only in a part of the studies. Two studies were case reports. A low risk of bias was observed. These findings advise further studies, ideally randomized, in order to better investigate the potential relationship between GFD and thyroid homeostasis. The level of evidence is not still sufficient to recommend GFD to patients with CAIT.
引用
收藏
页数:8
相关论文
共 50 条
  • [1] Gluten-free diet and autoimmune thyroiditis in patients with celiac disease. A prospective controlled study
    Metso, Saara
    Hyytia-Ilmonen, Henni
    Kaukinen, Katri
    Huhtala, Heini
    Jaatinen, Pia
    Salmi, Jorma
    Taurio, Jyrki
    Collin, Pekka
    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2012, 47 (01) : 43 - 48
  • [2] Specific Celiac Disease Antibodies in Children on a Gluten-Free Diet
    Esch, Caroline E. Hogen
    Wolters, Victorien M.
    Gerritsen, Susan A. M.
    Putter, Hein
    von Blomberg, B. Mary
    van Hoogstraten, Ingrid M. W.
    Houwen, Roderick H. J.
    van der Lely, Nico
    Mearin, M. Luisa
    PEDIATRICS, 2011, 128 (03) : 547 - 552
  • [3] Determination of gluten consumption in celiac disease patients on a gluten-free diet
    Syage, Jack A.
    Kelly, Ciaran P.
    Dickason, Matthew A.
    Cebolla Ramirez, Angel
    Leon, Francisco
    Dominguez, Remedios
    Sealey-Voyksner, Jennifer A.
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 2018, 107 (02) : 201 - 207
  • [4] Frequency of autoimmune thyroiditis in children with Celiac disease and effect of gluten free diet
    Rasheed, Javaria
    Hassan, Rushan
    Khalid, Muhammad
    Zafar, Fauzia
    PAKISTAN JOURNAL OF MEDICAL SCIENCES, 2020, 36 (06) : 1280 - 1284
  • [5] Characteristics of Hospitalized Patients With and Without Celiac Disease on a Gluten-Free Diet
    Eklund, Rachel
    Blackett, John W.
    Lee, Anne R.
    Green, Peter H. R.
    Lebwohl, Benjamin
    DIGESTIVE DISEASES AND SCIENCES, 2024, 69 (11) : 4116 - 4123
  • [6] Headache in Patients with Celiac Disease and Its Response to the Gluten-Free Diet
    Ameghino, Lucia
    Farez, Mauricio F.
    Wilken, Miguel
    Goicochea, Maria T.
    JOURNAL OF ORAL & FACIAL PAIN AND HEADACHE, 2019, 33 (03) : 294 - 300
  • [7] Adherence to a gluten-free diet in celiac disease patients from Paraguay
    Real-Delor, R. E.
    Chamorro-Aguilera, M. E.
    REVISTA DE GASTROENTEROLOGIA DE MEXICO, 2023, 88 (04): : 307 - 314
  • [8] The Effects of Gluten-Free Diet on Hypertransaminasemia in Patients with Celiac Disease
    Moghaddam, Mostafa Alavi
    Nejad, Mohammad Rostami
    Shalmani, Hamid Mohaghegh
    Rostami, Kamran
    Mojarad, Ehsan Nazemalhosseini
    Aldulaimi, David
    Zali, Mohammad Reza
    INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 2013, 4 (06) : 700 - 704
  • [9] Effect of gluten-free diet on autoimmune thyroiditis progression in patients with no symptoms or histology of celiac disease: a meta-analysis
    Piticchio, Tommaso
    Frasca, Francesco
    Malandrino, Pasqualino
    Trimboli, Pierpaolo
    Carrubba, Nunzia
    Tumminia, Andrea
    Vinciguerra, Federica
    Frittitta, Lucia
    FRONTIERS IN ENDOCRINOLOGY, 2023, 14
  • [10] Nutritional Deficiencies in Children with Celiac Disease Resulting from a Gluten-Free Diet: A Systematic Review
    Di Nardo, Giovanni
    Villa, Maria Pia
    Conti, Laura
    Ranucci, Giusy
    Pacchiarotti, Claudia
    Principessa, Luigi
    Raucci, Umberto
    Parisi, Pasquale
    NUTRIENTS, 2019, 11 (07)