Pd(OAc)2/DABCO-catalyzed Suzuki-Miyaura cross-coupling reaction in DMF

被引：67
作者：
Li, Jin-Heng [1 ]
Zhu, Qi-Ming [1 ]
Xie, Ye-Xiang [1 ]
机构：
[1] Hunan Normal Univ, Key Lab Chem Biol & Tradit Chinese Med Res, Minist Educ, Coll Chem & Chem Engn, Changsha 410081, Peoples R China
来源：
TETRAHEDRON | 2006年 / 62卷 / 47期
基金：
中国国家自然科学基金;
关键词：
Pd(OAc)(2)/DABCO; Suzuki-Miyaura cross-coupling reaction; aryl halide; arylboronic acids;
D O I：
10.1016/j.tet.2006.08.103
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The scope and limitations of the Pd(OAc)(2)/DABCO (1,4-diaza-bicyclo[2.2.2]octane)-catalyzed Suzuki-Miyaura cross-coupling reactions have been demonstrated. The results showed that the effect of solvent had a fundamental influence on the reaction. In the presence of Pd(OAc)2 and DABCO, both aryl bromides and aryl chlorides all worked well with arylboronic acids to form biaryls, heteroaryl-aryls, and bibeteroaryls in moderate to excellent yields using DMF as the solvent. Additionally, the reactions of aryl bromides were conducted under relatively mild conditions. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：10888 / 10895
页数：8
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