Adipose Tissue and Atherosclerosis

被引：14
|
作者：
Poledne, R. [1 ]
Lesna, I. Kralova [1 ]
Cejkova, S. [1 ]
机构：
[1] Inst Clin & Expt Med, Ctr Med Expt, Lab Atherosclerosis Res, Prague, Czech Republic
来源：
PHYSIOLOGICAL RESEARCH | 2015年 / 64卷
关键词：
Adipose tissue; Dyslipidemia; Inflammation; Macrophages; INSULIN-RESISTANCE; MACROPHAGE; FAT; OBESITY; LEPTIN; ACTIVATION; MONOCYTES; CELLS; LIVER; ACCUMULATION;
D O I：
10.33549/physiolres.933152
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
High-energy intake which exceeds energy expenditure leads to the accumulation of triglycerides in adipose tissue, predominantly in large-size adipocytes. This metabolic shift, which drives the liver to produce atherogenic dyslipidemia, is well documented. In addition, an increasing amount of monocytes/macrophages, predominantly the proinflammatory M1-type, cumulates in ectopic adipose tissue. The mechanism of this process, the turnover of macrophages in adipose tissue and their direct atherogenic effects all remain to be analyzed.
引用
收藏
页码：S395 / S402
页数：8
相关论文
共 50 条
  • [21] Adipose tissue inflammation
    Blueher, Matthias
    DIABETOLOGE, 2019, 15 (04): : 296 - 304
  • [22] Atherosclerosis Pathways are Activated in Pericoronary Adipose Tissue of Patients with Coronary Artery Disease
    Konwerski, Michal
    Gromadka, Agnieszka
    Arendarczyk, Adam
    Koblowska, Marta
    Iwanicka-Nowicka, Roksana
    Wilimski, Radoslaw
    Czub, Pawel
    Filipiak, Krzysztof Jerzy
    Hendzel, Piotr
    Zielenkiewicz, Piotr
    Opolski, Grzegorz
    Gasecka, Aleksandra
    Mazurek, Tomasz
    JOURNAL OF INFLAMMATION RESEARCH, 2021, 14 : 5419 - 5431
  • [23] Potential role of perivascular adipose tissue in modulating atherosclerosis
    Ahmadieh, Samah
    Kim, Ha Won
    Weintraub, Neal L.
    CLINICAL SCIENCE, 2020, 134 (01) : 3 - 13
  • [24] M1/M2 macrophage polarization in human obese adipose tissue
    Chylikova, Jaroslava
    Dvorackova, Jana
    Tauber, Zdenek
    Kamarad, Vojtech
    BIOMEDICAL PAPERS-OLOMOUC, 2018, 162 (02): : 79 - 82
  • [25] Identification of key genes and their association with immune infiltration in adipose tissue of obese patients: a bioinformatic analysis
    Wen, Jie
    Wang, Liwen
    ADIPOCYTE, 2022, 11 (01) : 401 - 412
  • [26] Multiple Roles of Sirtuin 6 in Adipose Tissue Inflammation
    Bae, Eun Ju
    Park, Byung-Hyun
    DIABETES & METABOLISM JOURNAL, 2023, 47 (02) : 164 - 172
  • [27] Macrophage infiltration into adipose tissue: initiation, propagation and remodeling
    Surmi, Bonnie K.
    Hasty, Alyssa H.
    FUTURE LIPIDOLOGY, 2008, 3 (05): : 545 - 556
  • [28] Adipose tissue regulatory T cells: differentiation and function
    Fooks, Allen N.
    Beppu, Lisa Y.
    Frias, Adolfo B.
    D'Cruz, Louise M.
    INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2023, 42 (05) : 323 - 333
  • [29] Overfeeding induces adipose tissue release of distinct mitochondria
    Goodman, Joshua H.
    Berland, Chloe
    Soni, Rajesh K.
    Ferrante Jr, Anthony W.
    CELL REPORTS, 2025, 44 (02):
  • [30] Role of Epicardial Adipose Tissue Secretome on Cardiovascular Diseases
    Leo, Sara
    Tremoli, Elena
    Ferroni, Letizia
    Zavan, Barbara
    BIOMEDICINES, 2023, 11 (06)
12345