Optical frequency comb based system for photonic refractive index sensor interrogation

被引:19
作者
Knoerzer, Markus [1 ]
Szydzik, Crispin [1 ,2 ]
Ren, Guanghui [1 ]
Huertas, Cesar S. [1 ]
Palmer, Sonya [1 ]
Phuong Tang [1 ]
Nguyen, Thach G. [1 ]
Bui, Lam [3 ]
Boes, Andreas [1 ]
Mitchell, Arnan [1 ]
机构
[1] RMIT Univ, Sch Engn, GPO Box 2476, Melbourne, Vic 3001, Australia
[2] Monash Univ, Australian Ctr Blood Dis, Alfred Med Res & Educ Precinct, 99 Commercial Rd, Melbourne, Vic 3004, Australia
[3] Cent Queensland Univ, Sch Engn & Technol, 120 Spencer St, Melbourne, Vic 3000, Australia
基金
澳大利亚研究理事会;
关键词
BIOSENSORS; SENSITIVITY; PERFORMANCE;
D O I
10.1364/OE.27.021532
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
In this contribution, we demonstrate how an optical frequency comb can be used to enhance the functionality of an integrated photonic biosensor platform. We show that if an optical frequency comb is used to sample the spectral response of a Mach-Zehnder interferometer and if the line spacing is arranged to sample the periodic response at 120 degrees intervals, then it is possible to combine these samples into a single measurement of the interferometer phase. This phase measurement approach is accurate, independent of the bias of the interferometer and robust against intensity fluctuations that are common to each of the comb lines. We demonstrate this approach with a simple silicon photonic interferometric refractive index sensor and show that the benefits of our approach can be obtained without degrading the lower limit of detection of 3.70x10(-7) RIU. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
引用
收藏
页码:21532 / 21545
页数:14
相关论文
共 35 条
  • [1] Cavity-enhanced dual-comb spectroscopy
    Bernhardt, Birgitta
    Ozawa, Akira
    Jacquet, Patrick
    Jacquey, Marion
    Kobayashi, Yohei
    Udem, Thomas
    Holzwarth, Ronald
    Guelachvili, Guy
    Haensch, Theodor W.
    Picque, Nathalie
    [J]. NATURE PHOTONICS, 2010, 4 (01) : 55 - 57
  • [2] Nanophotonic label-free biosensors for environmental monitoring
    Chocarro-Ruiz, Blanca
    Fernandez-Gavela, Adrian
    Herranz, Sonia
    Lechuga, Laura M.
    [J]. CURRENT OPINION IN BIOTECHNOLOGY, 2017, 45 : 175 - 183
  • [3] Coddington I, 2016, OPTICA, V3, P414, DOI [10.1364/optica.3.000414, 10.1364/OPTICA.3.000414]
  • [4] Soliton crystals in Kerr resonators
    Cole, Daniel C.
    Lamb, Erin S.
    Del'Haye, Pascal
    Diddams, Scott A.
    Papp, Scott B.
    [J]. NATURE PHOTONICS, 2017, 11 (10) : 671 - +
  • [5] All-optical phase modulation for integrated interferometric biosensors
    Dante, Stefania
    Duval, Daphne
    Sepulveda, Borja
    Belen Gonzalez-Guerrero, Ana
    Ramon Sendra, Jose
    Lechuga, Laura M.
    [J]. OPTICS EXPRESS, 2012, 20 (07): : 7195 - 7205
  • [6] Silicon-on-Insulator microring resonator for sensitive and label-free biosensing
    De Vos, Katrien
    Bartolozzi, Irene
    Schacht, Etienne
    Bienstman, Peter
    Baets, Roel
    [J]. OPTICS EXPRESS, 2007, 15 (12): : 7610 - 7615
  • [7] Silicon photonic wire biosensor array for multiplexed real-time and label-free molecular detection
    Densmore, A.
    Vachon, M.
    Xu, D. -X.
    Janz, S.
    Ma, R.
    Li, Y. -H.
    Lopinski, G.
    Delage, A.
    Lapointe, J.
    Luebbert, C. C.
    Liu, Q. Y.
    Cheben, P.
    Schmid, J. H.
    [J]. OPTICS LETTERS, 2009, 34 (23) : 3598 - 3600
  • [8] Last Advances in Silicon-Based Optical Biosensors
    Fernandez Gavela, Adrian
    Grajales Garcia, Daniel
    Ramirez, Jhonattan C.
    Lechuga, Laura M.
    [J]. SENSORS, 2016, 16 (03)
  • [9] Trends in photonic lab-on-chip interferometric biosensors for point-of-care diagnostics
    Gonzalez-Guerrero, A. B.
    Maldonado, J.
    Herranz, S.
    Lechuga, L. M.
    [J]. ANALYTICAL METHODS, 2016, 8 (48) : 8380 - 8394
  • [10] Subwavelength structures for silicon photonics biosensing
    Gonzalo Wanguemert-Perez, J.
    Hadij-ElHouati, Abdelfettah
    Sanchez-Postigo, Alejandro
    Leuermann, Jonas
    Xu, Dan-Xia
    Cheben, Pavel
    Ortega-Monux, Alejandro
    Halir, Robert
    Molina-Fernandez, Inigo
    [J]. OPTICS AND LASER TECHNOLOGY, 2019, 109 : 437 - 448