Case report of a Han ethnicity patient with Kaposi's sarcoma

被引:0
作者
Chen, Yongjun [1 ]
Huang, Changzheng [2 ]
Shi, Nian [1 ]
Nie, Gang [1 ]
机构
[1] Hubei Polytech Univ, Dept Dermatol, Huangshi Cent Hosp Edong Healthcare Grp, 141 Tianjin Rd, Huangshi, Hubei Province, Peoples R China
[2] Huazhong Univ, Dept Dermatol, Union Hosp, Tongji Med Coll, Wuhan, Peoples R China
来源
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2017年 / 10卷 / 02期
关键词
Classic Kaposi's sarcoma; Han ethnicity; HERPESVIRUS; INFECTION; CELLS;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Kaposi's sarcoma (KS) is known as multiple idiopathic hemorrhagic sarcoma. Its pathogenesis is complicated and related to abnormal angiogenesis, virus infections, etc. Human Herpes Virus-8 (HHV8) is increasingly linked to AIDS-associated KS. Herein, we reported a case of an 80-year-old male of Han ethnicity who developed dark red nodules on the inner popliteal fossa of his left leg without obvious predisposing causes two years ago. The nodules gradually increased in number, with unequal sizes, accompanied by discomfort. The patient was admitted to our hospital. Using clinical and tissue pathology combined with immunohistochemistry, the patient was diagnosed as the classical Kaposi's sarcoma of Han ethnicity. Local radiotherapy with electron beam ( total dose 5000 cgy, 6 million electron volts, 5 mm depth, 200 cgy each time, 25 times in total) was adopted for treatment. After 10 days of radiotherapy, the nodules diminished and partially degraded, while after one month of radiotherapy, most nodules gradually vanished.
引用
收藏
页码:3864 / 3867
页数:4
相关论文
共 10 条
  • [1] Classic Kaposi's sarcoma presenting first with gastrointestinal tract involvement in a HIV-negative Inuit male - A case report and review of the literature
    Balachandra, Brinda
    Tunitsky, Ellen
    Dawood, Shaheenah
    Hings, Ingrid
    Marcus, Victoria A.
    [J]. PATHOLOGY RESEARCH AND PRACTICE, 2006, 202 (08) : 623 - 626
  • [2] KAPOSIS SARCOMA-ASSOCIATED HERPESVIRUS INFECTS ENDOTHELIAL AND SPINDLE CELLS
    BOSHOFF, C
    SCHULZ, TF
    KENNEDY, MM
    GRAHAM, AK
    FISHER, C
    THOMAS, A
    MCGEE, JO
    WEISS, RA
    OLEARY, JJ
    [J]. NATURE MEDICINE, 1995, 1 (12) : 1274 - 1278
  • [3] Development of real-time PCR assays for detection and quantification of human bocavirus
    Choi, Jang-Hoon
    Chung, Yoon-Seok
    Kim, Ki-Soon
    Lee, Wan-Ji
    Chung, Il Yup
    Oh, Hee-Bok
    Kang, Chun
    [J]. JOURNAL OF CLINICAL VIROLOGY, 2008, 42 (03) : 249 - 253
  • [4] Histological variants of cutaneous Kaposi sarcoma
    Grayson, Wayne
    Pantanowitz, Liron
    [J]. DIAGNOSTIC PATHOLOGY, 2008, 3 (1)
  • [5] Human herpesvirus 8-derived viral IL-6 induces PTX3 expression in Kaposi's sarcoma cells
    Klouche, M
    Brockmeyer, N
    Knabbe, C
    Rose-John, S
    [J]. AIDS, 2002, 16 (08) : F9 - F18
  • [6] Rapid detection of human herpesvirus 8 DNA using loop-mediated isothermal amplification
    Kuhara, Tomoe
    Yoshikawa, Tetsushi
    Ihira, Masaru
    Watanabe, Daisuke
    Tamada, Yasuhiko
    Katano, Harutaka
    Asano, Yoshizo
    Matsumoto, Yoshinari
    [J]. JOURNAL OF VIROLOGICAL METHODS, 2007, 144 (1-2) : 79 - 85
  • [7] Landau HJ, 2001, CLIN CANCER RES, V7, P2263
  • [8] ROLE OF RADIOTHERAPY IN THE TREATMENT OF EPIDEMIC KAPOSIS-SARCOMA - EXPERIENCE WITH 65 CASES
    PICCINNO, R
    CACCIALANZA, M
    CUSINI, M
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1995, 32 (06) : 1000 - 1003
  • [9] The pleiotropic effects of Kaposi's sarcoma herpesvirus
    Schulz, TF
    [J]. JOURNAL OF PATHOLOGY, 2006, 208 (02) : 187 - 198
  • [10] Plasma HHV-8 Viral Load in HHV-8-Related Lymphoproliferative Disorders Associated With HIV Infection
    Simonelli, C.
    Tedeschi, R.
    Gloghini, A.
    Talamini, R.
    Bortolin, M. T.
    Berretta, M.
    Spina, M.
    Morassut, S.
    Vaccher, E.
    De Paoli, P.
    Carbone, A.
    Tirelli, U.
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2009, 81 (05) : 888 - 896