Orally exhaled nitric oxide levels as a marker of airway inflammation in childhood asthma

被引：0
作者：
Spallarossa, D [1 ]
Silvestri, M [1 ]
Battistini, E [1 ]
Macciò, IL [1 ]
Fregonese, B [1 ]
Biraghi, M [1 ]
Rossi, GA [1 ]
机构：
[1] Ist Giannina Gaslini, Div Pneumol, I-16148 Genoa, Italy
来源：
ASTHMA - A LINK BETWEEN ENVIRONMENT, IMMUNOLOGY, AND THE AIRWAYS | 1999年
关键词：
nitric oxide; childhood; allergic asthma;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Because nitric oxide (NO) release may be induced in bronchial epithelium by proinflammatory cytokines, it has been hypothesized that it may reflect the intensity of the inflammatory component of airway diseases. Indeed, increased NO levels in the expired air (e-NO) are present in asthma, and preliminary results suggest that this noninvasive test may be clinically useful in the management of patients with this disorder. Yet, questions have been raised concerning the technical aspects of e-NO measurement and concerning the real biological and clinical meaning of these bioactive species in exhaled air.
引用
收藏
页码：69 / 73
页数：5
相关论文
共 50 条
  • [41] Combined use of exhaled nitric oxide and airway hyperresponsiveness in characterizing asthma in a large population survey
    Henriksen, AH
    Lingaas-Holmen, T
    Sue-Chu, M
    Bjermer, L
    EUROPEAN RESPIRATORY JOURNAL, 2000, 15 (05) : 849 - 855
  • [42] Evaluation of Airway Inflammation in Compost Workers Exposed to Bioaerosols Using Exhaled Breath Condensate and Fractional Exhaled Nitric Oxide
    Hoffmeyer, F.
    van Kampen, V.
    Deckert, A.
    Neumann, H. -D.
    Buxtrup, M.
    Willer, E.
    Felten, C.
    Bruening, T.
    Raulf, M.
    Buenger, J.
    PULMONARY FUNCTION, 2015, 858 : 57 - 67
  • [43] Relationship between Exhaled Nitric Oxide and Levels of Asthma Control in Asthma Patients Treated with Inhaled Corticosteroid
    Han, Chang-Hee
    Park, You-Il
    Kwak, Hyun Jung
    Kim, Sa Il
    Kim, Tae Hyung
    Sohn, Jang Won
    Yoon, Ho Joo
    Shin, Dong Ho
    Park, Sung Soo
    Kim, Sang-Heon
    TUBERCULOSIS AND RESPIRATORY DISEASES, 2011, 71 (02) : 106 - 113
  • [44] The relation between nitric oxide levels in exhaled breath condensate and asthma control questionnaires in asthma patients
    Sazlidere, Huamettin
    Celikel, Serhat
    Inonu, Handan
    Doruk, Sibel
    Yilmaz, Ayse
    Ozyurt, Hseyin
    Erkorkmaz, Unal
    TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX, 2010, 58 (01): : 5 - 15
  • [45] Determinants of Exhaled Nitric Oxide Levels (FeNO) in Childhood Atopic Asthma: Evidence for Neonatal Respiratory Distress as a Factor Associated With Low FeNO Levels
    Ricciardolo, Fabio L. M.
    Silvestri, Michela
    Pistorio, Angela
    Strozzi, Mariachiara M.
    Tosca, Maria A.
    Bellodi, Simona C.
    Battistini, Elena
    Gardella, Chiara
    Rossi, Giovanni A.
    JOURNAL OF ASTHMA, 2010, 47 (07) : 810 - 816
  • [46] Exhaled nitric oxide levels in exacerbations of asthma, chronic obstructive pulmonary disease and pneumonia
    Al-Ali, MK
    Howarth, PH
    SAUDI MEDICAL JOURNAL, 2001, 22 (03) : 249 - 253
  • [47] Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in mild to moderately severe asthma
    Lim, S
    Jatakanon, A
    Meah, S
    Oates, T
    Chung, KF
    Barnes, PJ
    THORAX, 2000, 55 (03) : 184 - 188
  • [48] Using Fractional Exhaled Nitric Oxide Measurement in Clinical Asthma Management
    Rupani, Hitasha
    Kent, Brian D.
    CHEST, 2022, 161 (04) : 906 - 917
  • [49] Exhaled nitric oxide versus conventional tests for asthma
    Jay M. Portnoy
    Current Allergy and Asthma Reports, 2004, 4 (6) : 423 - 424
  • [50] Exhaled nitric oxide: A test for diagnosis and control of asthma?
    Rohit Katial
    Lora Stewart
    Current Allergy and Asthma Reports, 2007, 7 : 459 - 463
12345