Orally exhaled nitric oxide levels as a marker of airway inflammation in childhood asthma

被引：0
作者：
Spallarossa, D [1 ]
Silvestri, M [1 ]
Battistini, E [1 ]
Macciò, IL [1 ]
Fregonese, B [1 ]
Biraghi, M [1 ]
Rossi, GA [1 ]
机构：
[1] Ist Giannina Gaslini, Div Pneumol, I-16148 Genoa, Italy
来源：
ASTHMA - A LINK BETWEEN ENVIRONMENT, IMMUNOLOGY, AND THE AIRWAYS | 1999年
关键词：
nitric oxide; childhood; allergic asthma;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Because nitric oxide (NO) release may be induced in bronchial epithelium by proinflammatory cytokines, it has been hypothesized that it may reflect the intensity of the inflammatory component of airway diseases. Indeed, increased NO levels in the expired air (e-NO) are present in asthma, and preliminary results suggest that this noninvasive test may be clinically useful in the management of patients with this disorder. Yet, questions have been raised concerning the technical aspects of e-NO measurement and concerning the real biological and clinical meaning of these bioactive species in exhaled air.
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页码：69 / 73
页数：5
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