Papillomavirus assembly: An overview and perspectives

被引:20
作者
Cerqueira, Carla [1 ]
Schiller, John T. [1 ]
机构
[1] Natl Inst Hlth, Natl Canc Inst, Cellular Oncol Lab, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
Papillomavirus; Virion assembly; Pseudovirus; MINOR CAPSID PROTEIN; NUCLEAR IMPORT RECEPTORS; VIRUS-LIKE PARTICLES; TOBACCO-MOSAIC-VIRUS; BOVINE PAPILLOMAVIRUS; VIRAL-DNA; NEUTRALIZATION ASSAY; TYPE-11; INTERACTS; L1/L2; CAPSIDS; CELL-SURFACE;
D O I
10.1016/j.virusres.2016.11.010
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Papillomavirus life cycle is tightly coupled to epithelial cell differentiation, which has hindered the investigation of many aspects of papillomavirus biology, including virion assembly. The development of in vitro production methods of papillomavirus pseudoviruses, and the production of "native" virus in raft cultures have facilitated the study of some aspects of the assembly process. In this paper we review the current knowledge of papillomavirus assembly, directions for future research, and the implications of these studies on new therapeutic interventions. Published by Elsevier B.V.
引用
收藏
页码:103 / 107
页数:5
相关论文
共 75 条
[1]   Large Scale RNAi Reveals the Requirement of Nuclear Envelope Breakdown for Nuclear Import of Human Papillomaviruses [J].
Aydin, Inci ;
Weber, Susanne ;
Snijder, Berend ;
Ventayol, Pilar Samperio ;
Kuehbacher, Andreas ;
Becker, Miriam ;
Day, Patricia M. ;
Schiller, John T. ;
Kann, Michael ;
Pelkmans, Lucas ;
Helenius, Ari ;
Schelhaas, Mario .
PLOS PATHOGENS, 2014, 10 (05)
[2]   STRUCTURES OF BOVINE AND HUMAN PAPILLOMAVIRUSES - ANALYSIS BY CRYOELECTRON MICROSCOPY AND 3-DIMENSIONAL IMAGE-RECONSTRUCTION [J].
BAKER, TS ;
NEWCOMB, WW ;
OLSON, NH ;
COWSERT, LM ;
OLSON, C ;
BROWN, JC .
BIOPHYSICAL JOURNAL, 1991, 60 (06) :1445-1456
[3]   Nuclear localization but not PML protein is required for incorporation of the papillomavirus minor capsid protein L2 into virus-like particles [J].
Becker, KA ;
Florin, L ;
Sapp, C ;
Maul, GG ;
Sapp, M .
JOURNAL OF VIROLOGY, 2004, 78 (03) :1121-1128
[4]   Possible Role for Cellular Karyopherins in Regulating Polyomavirus and Papillomavirus Capsid Assembly [J].
Bird, Gregory ;
O'Donnell, Malinda ;
Moroianu, Junona ;
Garcea, Robert L. .
JOURNAL OF VIROLOGY, 2008, 82 (20) :9848-9857
[5]   The L2 minor capsid protein of low-risk human papillomavirus type 11 interacts with host nuclear import receptors and viral DNA [J].
Bordeaux, J. ;
Forte, S. ;
Harding, E. ;
Darshan, M. S. ;
Klucevsek, K. ;
Moroianu, J. .
JOURNAL OF VIROLOGY, 2006, 80 (16) :8259-8262
[6]  
Buck C.B., 2007, PRODUCTION PAPILLOMA
[7]  
Buck CB, 2005, METH MOLEC MED, V119, P445
[8]   Maturation of papillomavirus capsids [J].
Buck, CB ;
Thompson, CD ;
Pang, YYS ;
Lowy, DR ;
Schiller, JT .
JOURNAL OF VIROLOGY, 2005, 79 (05) :2839-2846
[9]   Efficient intracellular assembly of papillomaviral vectors [J].
Buck, CB ;
Pastrana, DV ;
Lowy, DR ;
Schiller, JT .
JOURNAL OF VIROLOGY, 2004, 78 (02) :751-757
[10]   Arrangement of L2 within the papillomavirus capsid [J].
Buck, Christopher B. ;
Cheng, Naiqian ;
Thompson, Cynthia D. ;
Lowy, Douglas R. ;
Steven, Alasdair C. ;
Schiller, John T. ;
Trus, Benes L. .
JOURNAL OF VIROLOGY, 2008, 82 (11) :5190-5197