Low-energy electron scattering from DNA including structural water and base-pair irregularities

被引：23

作者：

Caron, Laurent ^{[1
,2
]}

Sanche, Leon ^{[1
]}

Tonzani, Stefano ^{[3
]}

Greene, Chris H. ^{[4
,5
]}

机构：

[1] Univ Sherbrooke, Fac Med, Grp Rech Sci Radiat, Sherbrooke, PQ J1H 5N4, Canada

[2] Univ Sherbrooke, Dept Phys, Sherbrooke, PQ J1K 2R1, Canada

[3] Nat Publishing Grp, London N1 9XW, England

[4] Univ Colorado, Dept Phys, Boulder, CO 80309 USA

[5] Univ Colorado, JILA, Boulder, CO 80309 USA

来源：

PHYSICAL REVIEW A | 2009年 / 80卷 / 01期

基金：

加拿大自然科学与工程研究理事会;

关键词：

MOLECULE SCATTERING; DAMAGE;

D O I：

10.1103/PhysRevA.80.012705

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Elastic scattering of low-energy (0-13 eV) electrons from more realistic models of a DNA base-pair decamer is studied using multiple-scattering theory and T matrices obtained from ab initio R-matrix calculations. The models include two types of irregularities usually found in cellular DNA: base-pair mismatch and structural water molecules. Furthermore, we include in our calculation inelastic collisions. It is found that the basic interference patterns observed in the ideal and nonideal (i.e., more realistic) decamers are similar but have different amplitudes and are shifted in energy. Substantial inelastic losses, interestingly, cause pronounced local resonances, which could have an important influence in DNA strand breaks.

引用

页数：6

共 28 条

[1]

[Anonymous], An Open-Source Java Viewer for Chemical Structures in 3D

[2] Mechanism for damage to DNA by low-energy electrons [J].

Barrios, R ;

Skurski, P ;

Simons, J .

JOURNAL OF PHYSICAL CHEMISTRY B, 2002, 106 (33) :7991-7994

[3] Damage to model DNA fragments from very low-energy (<1 eV) electrons [J].

Berdys, J ;

Anusiewicz, I ;

Skurski, P ;

Simons, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (20) :6441-6447

[4] Multiple scattering approach to elastic low-energy electron collisions with the water dimer [J].

Bouchiha, D. ;

Caron, L. G. ;

Gorfinkiel, J. D. ;

Sanche, L. .

JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS, 2008, 41 (04)

[5]

Boudaïffa B, 2002, RADIAT RES, V157, P227, DOI 10.1667/0033-7587(2002)157[0227:CSFLEE]2.0.CO

[6]

[7] Induction of strand breaks by low-energy electrons (8-68 eV) in a self-assembled monolayer of oligonucleotides: Effective cross sections and attenuation lengths [J].

Cai, ZL ;

Dextraze, ME ;

Cloutier, P ;

Hunting, D ;

Sanche, L .

JOURNAL OF CHEMICAL PHYSICS, 2006, 124 (02)

[8] Multiple scattering approach to elastic electron collisions with molecular clusters [J].

Caprasecca, S. ;

Gorfinkiel, J. D. ;

Bouchiha, D. ;

Caron, L. G. .

JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS, 2009, 42 (09)

[9] Diffraction in resonant electron scattering from helical macromolecules: Effects of the DNA backbone [J].

Caron, L ;

Sanche, L .

PHYSICAL REVIEW A, 2005, 72 (03)

[10] Diffraction in resonant electron scattering from helical macromolecules:: A- and B-type DNA -: art. no. 032719 [J].

Caron, L ;

Sanche, L .

PHYSICAL REVIEW A, 2004, 70 (03) :032719-1

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