Schiff bases of poly-L-lysine and some compounds of the vitamin B-6 group. Influence of polypeptidic structure

被引：7
作者：
delVado, MAG
Gorostidi, GRE
Blanco, JGS
Blanco, FG
机构：
[1] UNIV ALCALA DE HENARES,DEPT PHYS CHEM,E-28871 ALCALA DE HENARES,SPAIN
[2] PONTIFICIA UNIV CATOLICA CHILE,FAC CHEM,SANTIAGO 22,CHILE
[3] UNIV COMPLUTENSE MADRID,FAC PHARM,E-28040 MADRID,SPAIN
来源：
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1997年 / 123卷 / 01期
关键词：
Schiff base; pyridoxal 5'-phosphate; 5'-deoxypyridoxal; pyridoxal; poly-L-lysine;
D O I：
10.1016/S1381-1169(97)00039-3
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The apparent rate constants of formation (k(1)) and hydrolysis (k(2)) of the Schiff bases formed between pyridoxal and poly-L-lysine has been fitted to a kinetic scheme that involves the different protonated species in the reaction medium and the individual rate constants of formation (k(1)(i)) and hydrolysis (k(2)(i)). A Bronsted plot with alpha = 0.67 is in accord with an acid catalytic intramolecular process. The effects of hydrophobic medium due to the presence of the macromolecule on the formation and hydrolysis of Schiff bases from FL, DPL and PLP with poly-L-lysine is discussed.
引用
收藏
页码：9 / 13
页数：5
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