Subclinical Inflammatory Response: Accelerated versus Standard Corneal Cross-Linking

被引:3
作者
Hedayatfar, Alireza [1 ,2 ]
Hashemi, Hassan [3 ]
Aghaei, Hossein [2 ]
Ashraf, Nahid [1 ]
Asgari, Soheila [4 ]
机构
[1] Noor Eye Hosp, Noor Ophthalmol Res Ctr, 96 Esfandiar Blvd,Valiasr Ave, Tehran 196865311, Iran
[2] Iran Univ Med Sci, Rassoul Akram Hosp, Tehran, Iran
[3] Noor Eye Hosp, Noor Res Ctr Ophthalm Epidemiol, Tehran, Iran
[4] Univ Tehran Med Sci, Sch Publ Hlth, Dept Epidemiol & Biostat, Tehran, Iran
关键词
Accelerated cross-linking; flare; standard cross-linking; subclinical inflammation; ANTERIOR-CHAMBER INFLAMMATION; FLARE; METER;
D O I
10.1080/09273948.2017.1420201
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To compare the subclinical inflammatory response (as measured by anterior chamber flare) induced after standard (3 mW/cm(2), 30 min) and accelerated (18 mW/cm(2), 5 min) corneal cross-linking (CXL). Methods: In this comparative, non-randomized study, patients with progressive keratoconus who underwent standard or accelerated CXL were studied. Laser flare photometery (FM-600; Kowa, Tokyo, Japan) was used to measure anterior chamber flare preoperatively and at 1 week, 1 month, 3 months, and 6 months after the procedure. Results: Sixty eyes of 60 patients were studied; 30 eyes in each group. Mean baseline flare values were 4.15 +/- 1.19 and 4.57 +/- 2.17 ph/ms in standard and accelerated groups, respectively (p = 0.228).and after surgery increased in all follow-up measurements in the both groups similarly (P > 0.05). Conclusion: Both standard and accelerated CXL results in induction of a subclinical inflammatory response that persists up to 6 month. The response was similar between the two groups.
引用
收藏
页码:513 / 516
页数:4
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