Rapid UHPLC Method Development for Omeprazole Analysis in a Quality-by-Design Framework and Transfer to HPLC Using Chromatographic Modelling

被引：0

作者：

Schmidt, Alexander H. ^{[1
,2
]}

Stanic, Mijo ^{[1
]}

机构：

[1] Deutsch Arzneimittel GmbH & Co KG, Steiner & Co, Berlin, Germany

[2] Free Univ Berlin, Inst Pharm, Berlin, Germany

来源：

LCGC EUROPE | 2014年 / 27卷 / 09期

关键词：

LIQUID-CHROMATOGRAPHY; SPACE; ROBUSTNESS; SEPARATION;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The aim of this study was to apply quality-by-design principles to build in a more scientific and risk-based multifactorial strategy in the development of an ultrahigh-pressure liquid chromatography (UHPLC) method for omeprazole and its related impurities.

引用

页码：466 / 478

页数：13

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