Phase-contrast microscopy at high x-ray energy with a laboratory setup

被引:34
作者
Endrizzi, Marco [1 ]
Vittoria, Fabio A. [1 ,2 ]
Diemoz, Paul C. [1 ,2 ]
Lorenzo, Rodolfo [3 ]
Speller, Robert D. [1 ]
Wagner, Ulrich H. [4 ]
Rau, Christoph [4 ]
Robinson, Ian K. [2 ,5 ]
Olivo, Alessandro [1 ,2 ]
机构
[1] UCL, Dept Med Phys & Bioengn, London WC1E 6BT, England
[2] Res Complex Harwell, Didcot OX11 0FA, Oxon, England
[3] UCL, Dept Civil Engn, London WC1E 6BT, England
[4] Diamond Light Source, Harwell OX11 0DE, Berks, England
[5] London Ctr Nanotechnol, London WC1H 0AH, England
基金
英国生物技术与生命科学研究理事会; 英国工程与自然科学研究理事会;
关键词
CODED-APERTURE; RETRIEVAL;
D O I
10.1364/OL.39.003332
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We report on the design and realization of an x-ray imaging system for quantitative phase-contrast microscopy at high x-ray energy with laboratory-scale instrumentation. Phase and amplitude were separated quantitatively at x-ray energies up to 80 keV with micrometric spatial resolution. The accuracy of the results was tested against numerical simulations, and the spatial resolution was experimentally quantified by measuring a Siemens star phase object. This simple setup should find broad application in those areas of x-ray imaging where high energy and spatial resolution are simultaneously required and in those difficult cases where the sample contains materials with similar x-ray absorption. (C) 2014 Optical Society of America
引用
收藏
页码:3332 / 3335
页数:4
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