GENETIC DIVERSITY OF HUMAN IMMUNODEFICIENCY VIRUS IN THE AMERICAS, WITH EMPHASIS ON THE VENEZUELAN EPIDEMICS

被引:0
作者
Rangel, Hector R.
Garzaro, Domingo
Pujol, Flor H. [1 ,2 ]
机构
[1] IVIC, CMBC, Mol Virol Lab, Caracas 1020A, Venezuela
[2] Univ Simon Bolivar, Caracas 1080, Venezuela
关键词
COMMERCIAL SEX WORKERS; INJECTING DRUG-USERS; HIV-1; SUBTYPE-B; MOLECULAR EPIDEMIOLOGY; SOUTH-AMERICA; DISEASE PROGRESSION; RECOMBINANT FORMS; TYPE-1; EPIDEMIC; LATIN-AMERICA; RISK-FACTORS;
D O I
暂无
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
Around 3 million people are thought to be infected with human immunodeficiency virus (HIV) in the Americas, and around 110000 in Venezuela, where HIV subtype distribution is quite homogenous, with mainly subtype B and few cases of non B subtypes or recombinant forms. The high frequency of subtype B in the Americas is probably due to a founder effect of this viral variant around 1960-1970. The epidemic might have started in Haiti and then was disseminated to other countries. The increase in frequency of non B subtypes in the Americas has been associated to several risk factors: intravenous drug abuse, commercial sex and sanitary and military movilizations. In countries like Cuba, Brasil and countries from the Southern Cone, the presence of non B subtype and recombinant forms is more frequent than in the rest of the region. This situation might mirror what we will find in all the Americas in the next decades.
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页码:163 / 169
页数:7
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