Epicardial Control of Myocardial Proliferation and Morphogenesis

被引：47
作者：
Sucov, Henry M. [1 ]
Gu, Ying [1 ]
Thomas, Simmy [1 ]
Li, Peng [1 ]
Pashmforoush, Mohammad [1 ]
机构：
[1] Univ So Calif, Keck Sch Med, Inst Med Genet, Los Angeles, CA 90033 USA
来源：
PEDIATRIC CARDIOLOGY | 2009年 / 30卷 / 05期
关键词：
Compact zone; Epicardium; Heart development; CORONARY-ARTERY FORMATION; X-RECEPTOR-ALPHA; CARDIAC DEVELOPMENT; HEART DEVELOPMENT; EMBRYONIC HEART; VASCULAR DEVELOPMENT; RETINOIC ACID; GROWTH-FACTOR; TGF-BETA; MYOCYTE PROLIFERATION;
D O I：
10.1007/s00246-009-9391-8
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The epicardium is a critical tissue that directs several aspects of heart development, particularly via the secretion of soluble factors. This review summarizes recent approaches that implicate the epicardium as the source of mitogenic factors promoting cardiomyocyte proliferation, as the source of instructive signals that direct compact zone organization (morphogenesis), and as the tissue that directs formation of the coronary vasculature.
引用
收藏
页码：617 / 625
页数：9
相关论文
共 68 条
  • [31] Novel tool to suppress cell proliferation in vivo demonstrates that myocardial and coronary vascular growth represent distinct developmental programs
    Lavine, Kory J.
    Schmid, Gregory J.
    Smith, Craig S.
    Ornitz, David M.
    [J]. DEVELOPMENTAL DYNAMICS, 2008, 237 (03) : 713 - 724
  • [32] Fibroblast growth factor signals regulate a wave of hedgehog activation that is essential for coronary vascular development
    Lavine, Kory J.
    White, Andrew C.
    Park, Changwon
    Smith, Craig S.
    Choi, Kyunghee
    Long, Fanxin
    Hui, Chi-chung
    Ornitz, David M.
    [J]. GENES & DEVELOPMENT, 2006, 20 (12) : 1651 - 1666
  • [33] REQUIREMENT FOR NEUREGULIN RECEPTOR ERBB2 IN NEURAL AND CARDIAC DEVELOPMENT
    LEE, KF
    SIMON, H
    CHEN, H
    BATES, B
    HUNG, MC
    HAUSER, C
    [J]. NATURE, 1995, 378 (6555) : 394 - 398
  • [34] FGF-16 is required for embryonic heart development
    Lu, Shun Yan
    Sheikh, Farah
    Sheppard, Patricia C.
    Fresnoza, Agnes
    Duckworth, Mary Lynn
    Detillieux, Karen A.
    Cattini, Peter A.
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 373 (02) : 270 - 274
  • [35] MANNER J, 1993, ANAT EMBRYOL, V187, P281
  • [36] STRUCTURAL DEVELOPMENT OF ENDOCARDIAL CUSHIONS
    MARKWALD, RR
    FITZHARRIS, TP
    MANASEK, FJ
    [J]. AMERICAN JOURNAL OF ANATOMY, 1977, 148 (01): : 85 - 119
  • [37] Epicardial retinoid X receptor α is required for myocardial growth and coronary artery formation
    Merki, E
    Zamora, L
    Raya, A
    Kawakami, Y
    Wang, JM
    Zhang, XX
    Burch, J
    Kubalak, SW
    Kaliman, P
    Belmonte, JCI
    Chien, KR
    Ruiz-Lozano, P
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (51) : 18455 - 18460
  • [38] Meyer D, 1997, DEVELOPMENT, V124, P3575
  • [39] MULTIPLE ESSENTIAL FUNCTIONS OF NEUREGULIN IN DEVELOPMENT
    MEYER, D
    BIRCHMEIER, C
    [J]. NATURE, 1995, 378 (6555) : 386 - 390
  • [40] Mikawa T., 1999, HEART DEV, P19
1234567