The outer membrane of Pseudomonas aeruginosa NCTC 6749 contributes to its tolerance to the essential oil of Melaleuca alternifolia (tea tree oil)

被引：191

作者：

Mann, CM ^{[1
]}

Cox, SD ^{[1
]}

Markham, JL ^{[1
]}

机构：

[1] Univ Western Sydney, Ctr Biostruct & Biomol Res, Sydney, NSW 2753, Australia

来源：

LETTERS IN APPLIED MICROBIOLOGY | 2000年 / 30卷 / 04期

关键词：

D O I：

10.1046/j.1472-765x.2000.00712.x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Pseudomonas aeruginosa is less susceptible to the antimicrobial properties of tea tree oil than many bacteria and its tolerance is considered to be due to its outer membrane. Polymyxin B nonapeptide (PMBN), which has no antibacterial action, was used to permeabilize the outer membrane. The addition of PMBN to Ps. aeruginosa NCTC 6749 markedly increased this organism's susceptibility to tea tree oil and to its normally inert hydrocarbons, p-cymene and gamma-terpinene.

引用

页码：294 / 297

页数：4

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