Dietary fruits and vegetables and cardiovascular diseases risk

被引:228
作者
Alissa, Eman M. [1 ]
Ferns, Gordon A. [2 ]
机构
[1] King Abdulaziz Univ, Fac Med, POB 12713, Jeddah 21483, Saudi Arabia
[2] Univ Brighton, Med Educ & Metab Med, Brighton & Sussex Med Sch, Brighton, E Sussex, England
关键词
Fruits; vegetables; cardiovascular diseases; hypertension; diabetes; hyperlipidemia; obesity; bioactive components; CORONARY-HEART-DISEASE; CELLULAR ANTIOXIDANT ACTIVITY; TYPE-2; DIABETES-MELLITUS; VITAMIN-C; BETA-CAROTENE; BLOOD-PRESSURE; ALL-CAUSE; MYOCARDIAL-INFARCTION; SECONDARY PREVENTION; MEDITERRANEAN DIET;
D O I
10.1080/10408398.2015.1040487
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Diet is likely to be an important determinant of cardiovascular disease (CVD) risk. In this article, we will review the evidence linking the consumption of fruit and vegetables and CVD risk. The initial evidence that fruit and vegetable consumption has a protective effect against CVD came from observational studies. However, uncertainty remains about the magnitude of the benefit of fruit and vegetable intake on the occurrence of CVD and whether the optimal intake is five portions or greater. Results from randomized controlled trials do not show conclusively that fruit and vegetable intake protects against CVD, in part because the dietary interventions have been of limited intensity to enable optimal analysis of their putative effects. The protective mechanisms of fruit and vegetables may not only include some of the known bioactive nutrient effects dependent on their antioxidant, anti-inflammatory, and electrolyte properties, but also include their functional properties, such as low glycemic load and energy density. Taken together, the totality of the evidence accumulated so far does appear to support the notion that increased intake of fruits and vegetables may reduce cardiovascular risk. It is clear that fruit and vegetables should be eaten as part of a balanced diet, as a source of vitamins, fiber, minerals, and phytochemicals. The evidence now suggests that a complicated set of several nutrients may interact with genetic factors to influence CVD risk. Therefore, it may be more important to focus on whole foods and dietary patterns rather than individual nutrients to successfully impact on CVD risk reduction. A clearer understanding of the relationship between fruit and vegetable intake and cardiovascular risk would provide health professionals with significant information in terms of public health and clinical practice.
引用
收藏
页码:1950 / 1962
页数:13
相关论文
共 149 条
[1]   Fruit and vegetable intakes, dietary antioxidant nutrients, and total mortality in Spanish adults:: findings from the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain) [J].
Agudo, Antonio ;
Cabrera, Laia ;
Amiano, Pilar ;
Ardanaz, Eva ;
Barricarte, Aurelio ;
Berenguer, Toni ;
Chirlaque, Maria D. ;
Dorronsoro, Miren ;
Jakszyn, Paula ;
Larranaga, Nerea ;
Martinez, Carmen ;
Navarro, Carmen ;
Quiros, Jose R. ;
Sanchez, Maria J. ;
Tormo, Maria J. ;
Gonzalez, Carlos A. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2007, 85 (06) :1634-1642
[2]   Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease - A randomized trial [J].
Albert, Christine M. ;
Cook, Nancy R. ;
Gaziano, J. Michael ;
Zaharris, Elaine ;
MacFadyen, Jean ;
Danielson, Eleanor ;
Buring, Julie E. ;
Manson, JoAnn E. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 299 (17) :2027-2036
[3]  
Anderson JW, 2000, AM J CLIN NUTR, V71, P472
[4]  
[Anonymous], 2010, DIET GUID AM 2010
[5]   A clinical trial of the effects of dietary patterns on blood pressure [J].
Appel, LJ ;
Moore, TJ ;
Obarzanek, E ;
Vollmer, WM ;
Svetkey, LP ;
Sacks, FM ;
Bray, GA ;
Vogt, TM ;
Cutler, JA ;
Windhauser, MM ;
Lin, PH ;
Karanja, N .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (16) :1117-1124
[6]  
Aviram M, 2002, DRUG EXP CLIN RES, V28, P49
[7]  
Bazzano LA, 2002, AM J CLIN NUTR, V76, P93
[8]   Intake of fruit, vegetables, and fruit juices and risk of diabetes in women [J].
Bazzano, Lydia A. ;
Li, Tricia Y. ;
Joshipura, Kamudi J. ;
Hu, Frank B. .
DIABETES CARE, 2008, 31 (07) :1311-1317
[9]   Dietary intake of fruits and vegetables and risk of cardiovascular disease [J].
Lydia A. Bazzano ;
Mary K. Serdula ;
Simin Liu .
Current Atherosclerosis Reports, 2003, 5 (6) :492-499
[10]   Increased potassium intake from fruit and vegetables or supplements does not lower blood pressure or improve vascular function in UK men and women with early hypertension: a randomised controlled trial [J].
Berry, Sarah E. ;
Mulla, Umme Z. ;
Chowienczyk, Philip J. ;
Sanders, Thomas A. B. .
BRITISH JOURNAL OF NUTRITION, 2010, 104 (12) :1839-1847