Newer Developments in the Synthesis of P-Heterocycles

The P-heterocyclic field forms a special part of organophosphorus chemistry, and is a special discipline within heterocyclic chemistry. The relevant results accumulated in the group of the author of this minireview in last 5 years are summarized. After surveying the conformational situation of cyclic phosphinates, their Microwave (MW)-assisted direct esterification and the T3P (R)-promoted esterification are discussed. The next chapters describe newer results regarding the interpretation and modelling of the rate enhancing effect of MWs, and on an important, but somewhat neglected field, the hydrolysis of phosphinates. New results on the ring enlargement of 5-membered unsaturated P-heterocycles to 6-ring species, as well as on the synthesis of 7-phosphanorbornene derivatives, and their refunctionalization are also included. Novel findings on the preparation of cyclic amides and imides are also explored. Last but not least, the user-friendly deoxygenations of cyclic phosphine oxides elaborated by us are shown. The reader will be able to discover green chemical considerations and accomplishments throughout the series of organophosphorus transformations reviewed.