MR imaging of Creutzfeldt-Jakob disease.

被引:0
作者
Gabaudan, C. [1 ]
Kaphan, E. [2 ]
Felician, O. [2 ]
Girard, N. [1 ]
机构
[1] CHU Timone, Serv Neuroradiol Diagnost & Intervent, F-13385 Marseille 5, France
[2] CHU Timone, Serv Neurol, F-13385 Marseille 5, France
关键词
Creutzfeldt-Jakob disease; MR; DIFFUSION-WEIGHTED MRI; STROKE-LIKE LESIONS; PULVINAR SIGN; DIAGNOSIS; ABNORMALITIES; INVOLVEMENT; SENSITIVITY; PATTERNS;
D O I
10.1016/S0181-9801(09)74608-1
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Creutzfeldt-Jakob disease is a fatal neurodegenerative disease characterized by an abnormal accumulation of human prion protein PrPSc. It causes a rapidly progressive dementia syndrome. The imaging work-up is based on MRI which often discloses the typical disease anomaly seen as high signal intensity in the basal ganglia and cerebral cortex on Flair sequences and/or more readily on diffusion weighted sequences. This work recalls our fundamental knowledge concerning this disease and presents MRI data from 7 cases and a review of the literature.
引用
收藏
页码:171 / 185
页数:15
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