Combining chemical analysis and ecotoxicity to determine environmental exposure and to assess risk from sulfonamides

被引：138

作者：

Jesus Garcia-Galan, Ma ^{[1
]}

Silvia Diaz-Cruz, M. ^{[1
]}

Barcelo, Damia ^{[1
,2
]}

机构：

[1] CSIC, Spanish Council Sci Res, Inst Environm Assessment & Water Studies IDAEA, Dept Environm Chem, E-08034 Barcelona, Spain

[2] Univ Girona, Inst Water Res ICRA, E-17003 Girona, Spain

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2009年 / 28卷 / 06期

关键词：

Antibiotic; Antimicrobial resistance; Chemical analysis; Drug release; Ecotoxicity; Environmental exposure; Environmental hazard; Environmental risk; Risk assessment; Sulfonamide; TANDEM MASS-SPECTROMETRY; INDUCED COMMUNITY TOLERANCE; SEWAGE-TREATMENT PLANTS; SOIL MICROBIAL ACTIVITY; LIQUID-CHROMATOGRAPHY; AQUATIC ENVIRONMENT; VETERINARY ANTIBIOTICS; HUMAN PHARMACEUTICALS; ANTIBACTERIAL AGENTS; MANURE;

D O I：

10.1016/j.trac.2009.04.006

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In recent years, concern regarding the environmental presence of sulfonamides (SAs) and other species of antibiotics has increased considerably due mainly to the potential spread of antimicrobial resistance in the different bacterial communities. However, many other ecotoxicological effects due to the release of these drugs in the different ecosystems may also be taking place. Analytical chemistry plays an important role in evaluating ecotoxicity through unequivocal identification and precise quantification of target compounds even when concentrations are very small. We aim to review all the studies carried out to date on potential environmental hazards posed by the SAs and to comment on the usefulness of chemical analysis in this application. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：804 / 819

页数：16

共 67 条

[1] Biodegradability of cefotiam, ciprofloxacin, meropenem, penicillin G, and sulfamethoxazole and inhibition of waste water bacteria [J].

Al-Ahmad, A ;

Daschner, FD ;

Kümmerer, K .

ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1999, 37 (02) :158-163

[2] Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment [J].

Andreozzi, R ;

Marotta, R ;

Paxeus, N .

CHEMOSPHERE, 2003, 50 (10) :1319-1330

[3]

[Anonymous], 1990, OJ, VL224, P1

[4] Toxicity and biodegradability of sulfonamides and products of their photocatalytic degradation in aqueous solutions [J].

Baran, Wojciech ;

Sochacka, Jolanta ;

Wardas, Wladyslaw .

CHEMOSPHERE, 2006, 65 (08) :1295-1299

[5] Occurrence of sulfonamide antimicrobials in private water wells in Washington County, Idaho, USA [J].

Batt, Angela L. ;

Snow, Daniel D. ;

Aga, Diana S. .

CHEMOSPHERE, 2006, 64 (11) :1963-1971

[6] Photochemical fate of sulfa drugs in the aquatic environment: Sulfa drugs containing five-membered heterocyclic groups [J].

Boreen, AL ;

Arnold, WA ;

McNeill, K .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2004, 38 (14) :3933-3940

[7] The sorption and transport of a sulphonamide antibiotic in soil systems [J].

Boxall, ABA ;

Blackwell, P ;

Cavallo, R ;

Kay, P ;

Tolls, J .

TOXICOLOGY LETTERS, 2002, 131 (1-2) :19-28

[8] Effects of 25 pharmaceutical compounds to Lemna gibba using a seven-day static-renewal test [J].

Brain, RA ;

Johnson, DJ ;

Richards, SM ;

Sanderson, H ;

Sibley, PK ;

Solomon, KR .

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 2004, 23 (02) :371-382

[9] Herbicidal Effects of Sulfamethoxazole in Lemna gibba: Using p-Aminobenzoic Acid As a Biomarker of Effect [J].

Brain, Richard A. ;

Ramirez, Alejandro J. ;

Fulton, Barry A. ;

Chambliss, C. Kevin ;

Brooks, Bryan W. .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2008, 42 (23) :8965-8970

[10] Prioritising veterinary medicines according to their potential indirect human exposure and toxicity profile [J].

Capleton, AC ;

Courage, C ;

Rumsby, P ;

Holmes, P ;

Stutt, E ;

Boxall, ABA ;

Levy, LS .

TOXICOLOGY LETTERS, 2006, 163 (03) :213-223

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