Heart rate: clinical variable and risk marker

被引：3

作者：

Custodis, F. ^{[1
]}

Reil, J. -C. ^{[1
]}

Schirmer, S. H. ^{[1
]}

Adam, O. ^{[1
]}

Moehlenkamp, S. ^{[2
]}

Laufs, U. ^{[1
]}

Boehm, M. ^{[1
]}

机构：

[1] Univ Klinikum Saarlandes, Klin Innere Med 3, D-66421 Homburg, Germany

[2] Krankenhaus Bethanien, Abt Kardiol, Moers, Germany

来源：

DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT | 2014年 / 139卷 / 33期

关键词：

heart rate; cardiovascular risk; risk marker; risk factor; MULTIPLE ORGAN DYSFUNCTION; CORONARY-ARTERY-DISEASE; VENTRICULAR SYSTOLIC DYSFUNCTION; RATE REDUCTION; CARDIOVASCULAR MORTALITY; MYOCARDIAL-INFARCTION; HYPERTENSIVE PATIENTS; ENDOTHELIAL FUNCTION; PROGNOSTIC-FACTOR; EUROPEAN-SOCIETY;

D O I：

10.1055/s-0034-1370223

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart rate is an easily accessible clinical variable with wide-ranging prognostic impact. Elevated resting heart rate predicts an elevated cardiovascular risk. Epidemiological studies demonstrate a relevant association between heart rate and survival in individuals without diagnosed cardiovascular disease and with cardiovascular disease like hypertension, coronary artery disease (CAD) and heart failure. Whereas a goal directed pharmacological heart rate reduction is not supported by clinical evidence for primary prevention it plays a prognostic role for patients with CAD and chronic heart failure. Moreover heart rate can be characterized as an independent risk factor for patients with heart failure and potentially for those with CAD. As a result the common guidelines recommend heart rate reduction as a target of therapy. © Georg Thieme Verlag KG • Stuttgart • New York.

引用

页码：1661 / 1672

页数：12

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