Brain SPECT in Sydenham's chorea in remission

被引：7

作者：

Beato, Rogerio ^{[1
]}

Siqueira, Cristiano Ferrari ^{[1
]}

Marroni, Belmonte J. ^{[1
]}

Boanova, Luciane Guerra ^{[1
]}

de Lima, Carla Flavia ^{[1
]}

Maia, Debora Palma ^{[1
]}

Nattan, Marcio ^{[1
]}

Cardoso, Francisco ^{[1
]}

机构：

[1] Univ Fed Minas Gerais, Neurol Serv, Movement Disorders Unit, Dept Internal Med, Belo Horizonte, MG, Brazil

来源：

MOVEMENT DISORDERS | 2014年 / 29卷 / 02期

关键词：

putamen; SPECT; Sydenham's chorea; basal ganglia; perfusion; STRIATAL HYPERMETABOLISM; ADULT PATIENTS; PET; MRI; TOMOGRAPHY; DISEASE;

D O I：

10.1002/mds.25721

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background Sydenham's chorea, a major manifestation of rheumatic fever, is characterized by chorea, behavioral changes, and cognitive dysfunction. Perfusion changes in the basal ganglia are the most frequent imaging findings observed in patients with Sydenham's chorea. Methods Twelve adult women with Sydenham's chorea in remission underwent brain single-photon emission computed tomography (SPECT). Their scans underwent a quantification process to evaluate the perfusion of Brodmann's areas of the frontal lobes and basal ganglia. The results were compared with the findings from a control group that was matched by age. Results A pattern of hyperperfusion in the left putamen was observed in the patient group (P = 0.02). No significant difference was observed in relation to other brain regions. Conclusions The findings of brain SPECT suggest that perfusion abnormalities of the basal ganglia may persist even after the remission of abnormal movements in patients with Sydenham's chorea. (c) 2013 International Parkinson and Movement Disorder Society

引用

页码：256 / 258

页数：3

共 27 条

[1] Sydenham's chorea: Positron emission tomographic (PET) scan studies [J].