Functional genomics - Recognizing DNA in the library

被引:51
|
作者
Nair, SK
Burley, SK
机构
[1] Rockefeller Univ, Lab Mol Biophys, New York, NY 10021 USA
[2] Rockefeller Univ, Howard Hughes Med Inst, New York, NY 10021 USA
关键词
D O I
10.1038/35008182
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Basic helix-loop-helix (bHLH) transcription factors are proteins involved in regulating gene expression. For this they have to recognize target sequences in DNA. A combinatorial approach not only allows more detailed study of DNA recognition and binding by bHLH proteins, but will also be more broadly applicable.
引用
收藏
页码:715 / 718
页数:4
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